Predicted protein targets (top 18)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | TSHR | P16473 | 9/20 | 0.77 |
| ▸ | HPGD | P15428 | 1/20 | 0.61 |
| ▸ | ALDH1A1 | P00352 | 5/20 | 0.47 |
| ▸ | CYP3A4 | P08684 | 3/20 | 0.47 |
| ▸ | ATM | Q13315 | 2/20 | 0.46 |
| ▸ | TDP1 | Q9NUW8 | 2/20 | 0.45 |
| ▸ | TP53 | P04637 | 2/20 | 0.43 |
| ▸ | HIF1A | Q16665 | 2/20 | 0.43 |
| ▸ | HSD17B10 | Q99714 | 1/20 | 0.43 |
| ▸ | HCAR2 | Q8TDS4 | 3/20 | 0.41 |
| ▸ | THRB | P10828 | 1/20 | 0.41 |
| ▸ | CA2 | P00918 | 1/20 | 0.40 |
| ▸ | RECQL | P46063 | 1/20 | 0.38 |
| ▸ | LMNA | P02545 | 1/20 | 0.37 |
| ▸ | MAPT | P10636 | 1/20 | 0.36 |
| ▸ | RAB9A | P51151 | 1/20 | 0.36 |
| ▸ | NPSR1 | Q6W5P4 | 1/20 | 0.36 |
| ▸ | MAPK1 | P28482 | 1/20 | 0.36 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL1480795 | 0.93 | TSHR (0.87) | TSHRHPGDALDH1A1CYP3A4ATM | |
| SCHEMBL7620022 | 0.90 | TSHR (0.81) | TSHRHPGDALDH1A1CYP3A4ATM | |
| SCHEMBL31661158 | 0.90 | TSHR (0.81) | TSHRHPGDALDH1A1CYP3A4ATM | |
| SCHEMBL19456761 | 0.90 | TSHR (0.87) | TSHRHPGDALDH1A1CYP3A4ATM | |
| SCHEMBL31661155 | 0.89 | TSHR (0.79) | TSHRHPGDALDH1A1CYP3A4ATM | |
| SCHEMBL31448301 | 0.89 | TSHR (0.79) | TSHRHPGDALDH1A1CYP3A4ATM | |
| SCHEMBL1741907 | 0.89 | TSHR (0.73) | TSHRHPGDALDH1A1CYP3A4ATM | |
| SCHEMBL41831 | 0.89 | TSHR (0.64) | TSHRHPGDALDH1A1CYP3A4ATM | |
| SCHEMBL729516 | 0.89 | TSHR (0.79) | TSHRHPGDALDH1A1CYP3A4ATM | |
| SCHEMBL729740 | 0.89 | TSHR (0.79) | TSHRHPGDALDH1A1CYP3A4ATM |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 3 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-0429009-B1 | Method of making shaped articles | MITSUBISHI RAYON CO (JP) | 1996-10-23 | — | — | EP | disclosed |
| US-5503897-A | POLYMER LAYER DERIVED FROM MULTIFUNCTIONAL MONOMER(S) HAVING AT LEAST TWO (METH)ACRYLOYLOXY GROUPS PER MOLECULE; UV RADIATION THROUGH CONTROLLING MATERIAL; ALKALI TREATMENT | MITSUBISHI RAYON CO., LTD. (JP) | 1996-04-02 | — | — | US | disclosed |
| EP-0429009-A2 | Method of making shaped articles | MITSUBISHI RAYON CO., LTD. (JP) | 1991-05-29 | — | — | EP | disclosed |