Predicted protein targets (top 1)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.31 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL18318828 | 0.73 | — | — | |
| SCHEMBL2877266 | 0.67 | POLB (0.36) | — | |
| SCHEMBL9004833 | 0.66 | TAAR1 (0.49) | — | |
| SCHEMBL7489573 | 0.66 | TAAR1 (0.49) | — | |
| SCHEMBL9004827 | 0.66 | TAAR1 (0.49) | — | |
| SCHEMBL8634605 | 0.65 | SMN1; SMN2 (0.54) | SMN1; SMN2 | |
| SCHEMBL30292048 | 0.65 | SMN1; SMN2 (0.54) | SMN1; SMN2 | |
| SCHEMBL27354248 | 0.64 | SMN1; SMN2 (0.34) | SMN1; SMN2 | |
| SCHEMBL8527470 | 0.64 | CYP1A2 (0.47) | — | |
| SCHEMBL16869473 | 0.61 | CYP3A4 (0.38) | — |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-5491152-A | Derivatives of cyclic ethers and sulfides for the treatment of atherosclerosis | THE DU PONT MERCK PHARMACEUTICAL COMPANY (US) | 1996-02-13 | — | — | US | disclosed |