Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | SLC6A2 | P23975 | 3/20 | 0.43 |
| ▸ | SLC6A4 | P31645 | 3/20 | 0.43 |
| ▸ | KCNH2 | Q12809 | 3/20 | 0.43 |
| ▸ | KMT2A | Q03164 | 2/20 | 0.38 |
| ▸ | POLB | P06746 | 1/20 | 0.36 |
| ▸ | KLKB1 | P03952 | 1/20 | 0.35 |
| ▸ | DRD1 | P21728 | 1/20 | 0.33 |
| ▸ | KCNN4 | O15554 | 2/20 | 0.32 |
| ▸ | SMN1; SMN2 | Q16637 | 3/20 | 0.32 |
| ▸ | MAPK1 | P28482 | 1/20 | 0.32 |
| ▸ | HTT | P42858 | 1/20 | 0.31 |
| ▸ | NFE2L2 | Q16236 | 1/20 | 0.31 |
| ▸ | SLC6A3 | Q01959 | 1/20 | 0.31 |
| ▸ | L3MBTL1 | Q9Y468 | 3/20 | 0.31 |
| ▸ | ALDH1A1 | P00352 | 2/20 | 0.31 |
| ▸ | MEN1 | O00255 | 1/20 | 0.30 |
| ▸ | TSHR | P16473 | 1/20 | 0.30 |
| ▸ | TDP1 | Q9NUW8 | 1/20 | 0.30 |
| ▸ | KDM4E | B2RXH2 | 1/20 | 0.30 |
| ▸ | KDM1A | O60341 | 1/20 | 0.30 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL25767325 | 0.81 | SLC6A2 (0.46) | SLC6A2SLC6A4KCNH2KMT2APOLB | |
| SCHEMBL28204897 | 0.78 | KDM4E (0.39) | KCNH2KMT2APOLBSMN1; SMN2NFE2L2 | |
| SCHEMBL16797182 | 0.77 | SLC6A2 (0.46) | SLC6A2SLC6A4KCNH2KMT2APOLB | |
| SCHEMBL900189 | 0.77 | SLC6A2 (0.46) | SLC6A2SLC6A4KCNH2KMT2APOLB | |
| SCHEMBL18150337 | 0.77 | SLC6A2 (0.46) | SLC6A2SLC6A4KCNH2KMT2APOLB | |
| SCHEMBL18149715 | 0.77 | SLC6A2 (0.46) | SLC6A2SLC6A4KCNH2KMT2APOLB | |
| SCHEMBL12474311 | 0.77 | KLKB1 (0.35) | SLC6A2SLC6A4KCNH2KMT2APOLB | |
| SCHEMBL20534794 | 0.73 | SLC6A2 (0.43) | SLC6A2SLC6A4KCNH2KMT2APOLB | |
| SCHEMBL900277 | 0.73 | SCN9A (0.34) | SLC6A2SLC6A4KCNH2SLC6A3ALDH1A1 | |
| SCHEMBL30540309 | 0.71 | KMT2A (0.46) | SLC6A2SLC6A4KCNH2KMT2APOLB |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-2621922-A1 | A PROCESS FOR THE SYNTHESIS OF THIO-TRIAZOLO-GROUP CONTAINING COMPOUNDS | BASF SE (DE) | 2013-08-07 | — | — | EP | disclosed |
| WO-2012041858-A1 | A PROCESS FOR THE SYNTHESIS OF THIO-TRIAZOLO-GROUP CONTAINING COMPOUNDS | BASF SE (DE) | 2012-04-05 | — | — | WO | disclosed |