SCHEMBL9008151

SCHEMBL9008151

COP(OCc1ccccc1)OC(C)C

nearest known ligand 0.39

Predicted protein targets (top 20)

geneUniProtsupporting neighboursconfidence
TSHR P16473 3/20 0.39
HPGD P15428 3/20 0.38
ALDH1A1 P00352 2/20 0.38
MAPK1 P28482 2/20 0.38
LMNA P02545 1/20 0.38
HTT P42858 1/20 0.38
IDO1 P14902 1/20 0.36
AGXT P21549 1/20 0.35
CA1 P00915 1/20 0.35
CA2 P00918 1/20 0.35
CA9 Q16790 1/20 0.35
MAOB P27338 1/20 0.35
SLC6A2 P23975 3/20 0.35
SLC6A4 P31645 2/20 0.35
SLC6A3 Q01959 2/20 0.35
KMT2A Q03164 2/20 0.35
TAAR1 Q96RJ0 2/20 0.34
MAOA P21397 1/20 0.34
SIGMAR1 Q99720 1/20 0.34
CYP2A6 P11509 1/20 0.34

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL18544225 0.91 TSHR (0.43) TSHRHPGDALDH1A1MAPK1LMNA
SCHEMBL9052472 0.85 TSHR (0.48) TSHRALDH1A1MAPK1LMNAIDO1
SCHEMBL383496 0.85 TSHR (0.48) TSHRALDH1A1MAPK1LMNAIDO1
SCHEMBL9407989 0.76 MAOB (0.43) TSHRHPGDALDH1A1MAPK1LMNA
SCHEMBL7334884 0.76 TSHR (0.41) TSHRHPGDALDH1A1MAPK1LMNA
Phosphine SCHEMBL21501010 0.76 TSHR (0.40) TSHRALDH1A1MAPK1IDO1AGXT
SCHEMBL194803 0.76 TSHR (0.57) TSHRALDH1A1MAPK1LMNAIDO1
SCHEMBL4869141 0.75 TSHR (0.39) TSHRHPGDALDH1A1MAPK1LMNA
SCHEMBL1552017 0.75 TSHR (0.39) TSHRHPGDALDH1A1MAPK1LMNA
SCHEMBL11687302 0.74 TSHR (0.55) TSHRALDH1A1MAPK1LMNAIDO1

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 120 patents — showing the first 20. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
EP-0331095-B1 Improving stability at moderate temperatures of motor vehicle components shaped from polyvinyl chloride resin compositions WITCO CORP (US) 1996-10-09 EP disclosed
EP-0313676-B1 Bis-(2,2,6,6-tetramethyl-piperidyl) diimides as light stabilizers for synthetic polymers ADEKA ARGUS CHEMICAL CO LTD (JP) 1994-01-26 EP disclosed
EP-0184203-B1 VINYL BENZYL 2,2,6,6-TETRAMETHYL PIPERIDINES ADEKA ARGUS CHEMICAL CO., Ltd. (JP) 1992-04-15 EP disclosed
EP-0188236-B1 POLYACETAL RESIN COMPOSITIONS HAVING IMPROVED RESISTANCE TO DETERIORATION WHEN EXPOSED TO LIGHT AND CONTAINING ALKYLIDENE BIS(BENZOTRIAZOLYL PHENOLS) ADEKA ARGUS CHEMICAL CO., Ltd. (JP) 1992-04-01 EP disclosed
EP-0209126-B1 HYDROCARBYL(POLYPHENOL)-POLY(2,2,6,6-TETRAMETHYL PIPERIDYL-1,3,5-TRIAZINES) AS STABILIZERS FOR SYNTHETIC POLYMER COMPOSITIONS ADEKA ARGUS CHEMICAL CO., Ltd. (JP) 1992-01-02 EP disclosed
EP-0217149-B1 POLY(2,2,6,6-TETRAMETHYLPIPERIDYLAMINOSPIROGLYCOLETHER-1,3,5-TRIAZINES) ADEKA ARGUS CHEMICAL CO., Ltd. (JP) 1991-01-30 EP disclosed
EP-0176106-B1 N,N',N-TRIS((2,2,6,6-TETRAMETHYL-4-PIPERIDYL)TRIAZINYL)-UNDECANE TRIAMINES AS STABILIZERS FOR SYNTHETIC POLYMERS ADEKA ARGUS CHEMICAL CO., Ltd. (JP) 1990-11-22 EP disclosed
US-4957954-A TETRAMETHYPIPERIDINYL COMPOUND AND PERCHLORATE ADEKA ARGUS CHEMICAL CO., LTD. (JP) 1990-09-18 US disclosed
EP-0047894-B2 HOMOGENEOUS STORAGE-STABLE LIQUID BARIUM-CADMIUM-TRIPHOSPHITE STABILIZER SYSTEMS FOR POLYVINYL CHLORIDE RESINS Argus Chemical Corporation (US) 1990-09-05 EP disclosed
US-4950704-A DIKETONE AS HEAT STABILIZER ARGUS CHEMICAL CORPORATION (US) 1990-08-21 US disclosed
EP-0024919-A2 Process for providing monovalent and polyvalent metal, particularly antimony, mercaptocarboxylic acid ester salts; monovalent and polyvalent metal mercaptocarboxylic acid salts; polyol mercaptocarboxylic acid monoesters, and esters of such polyol mercaptocarboxylic acid esters with a mercaptocarboxylic acid; stabilizer compositions for polyvinyl chloride resins comprising such compounds; and polyvinyl chloride resin compositions comprising a stabilizing amount of such compounds Mack, Gerry (US) 1981-03-11 EP disclosed
US-4222931-A Stabilizers for synthetic polymers comprising 2,2,6,6-tetramethyl-4-piperidyl ether alcohol or ether, phosphonic acid ester and phenolic antioxidant ARGUS CHEMICAL CORPORATION (US) 1980-09-16 US disclosed
US-4219463-A Stabilizers for synthetic polymers comprising 2,2,6,6-tetramethyl-4-piperidyl carboxylic acid ester, β-thioalkyl propionic acid ester and phenol ARGUS CHEMICAL CORPORATION (US) 1980-08-26 US disclosed
US-4210577-A Stabilizers for synthetic polymers comprising 2,2,6,6-tetramethyl-4-piperidyl carboxylic acid ester, phosphonic acid ester and phenol ARGUS CHEMICAL CORPORATION (US) 1980-07-01 US disclosed
US-4209431-A OXIDATION AND HEAT RESISTANCE WITCO CHEMICAL CORPORATION (US) 1980-06-24 US disclosed
US-4110306-A Stabilizers for synthetic polymers comprising 2,2,6,6-tetramethyl-4-piperidyl carboxylic acid ester, a triphosphite, and an acid phosphite or salt thereof ARGUS CHEMICAL CORPORATION (US) 1978-08-29 US disclosed
US-4105627-A MERCAPTOHETEROCYCLIC RESIN STABILIZERS ARGUS CHEMICAL CORPORATION (US) 1978-08-08 US disclosed
US-4080364-A Stabilization of polyolefins against degradative deterioration as a result of exposure to light and air at elevated temperatures ARGUS CHEMICAL CORPORATION (US) 1978-03-21 US disclosed
US-3997551-A OXIDATION RESISTANCE, STABILIZE POLYMERS ARGUS CHEMICAL CORPORATION (US) 1976-12-14 US disclosed
US-3991139-A NORBORNENE DERIVATIVES, PHENOLS, ESTER THIOETHERS SHOWA DENKO KABUSHIKI KAISHA (JA) 1976-11-09 US disclosed