Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | FFAR1 | O14842 | 1/20 | 0.76 |
| ▸ | FFAR4 | Q5NUL3 | 1/20 | 0.76 |
| ▸ | FAAH | O00519 | 5/20 | 0.64 |
| ▸ | NFKB1 | P19838 | 1/20 | 0.58 |
| ▸ | NFKB2 | Q00653 | 1/20 | 0.58 |
| ▸ | RELA | Q04206 | 1/20 | 0.58 |
| ▸ | TRPV1 | Q8NER1 | 2/20 | 0.47 |
| ▸ | KMT2A | Q03164 | 2/20 | 0.46 |
| ▸ | MEN1 | O00255 | 1/20 | 0.46 |
| ▸ | CYP3A4 | P08684 | 1/20 | 0.46 |
| ▸ | TERT | O14746 | 3/20 | 0.46 |
| ▸ | MAPT | P10636 | 2/20 | 0.46 |
| ▸ | BLM | P54132 | 2/20 | 0.46 |
| ▸ | HSD17B10 | Q99714 | 2/20 | 0.46 |
| ▸ | GPR84 | Q9NQS5 | 2/20 | 0.46 |
| ▸ | FABP4 | P15090 | 2/20 | 0.46 |
| ▸ | GMNN | O75496 | 1/20 | 0.46 |
| ▸ | USP2 | O75604 | 1/20 | 0.46 |
| ▸ | LMNA | P02545 | 1/20 | 0.46 |
| ▸ | CYP1A2 | P05177 | 1/20 | 0.46 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL10875401 | 1.00 | FFAR1 (0.76) | FFAR1FFAR4FAAHNFKB1NFKB2 | |
| SCHEMBL20021280 | 1.00 | FFAR1 (0.76) | FFAR1FFAR4FAAHNFKB1NFKB2 | |
| SCHEMBL7204568 | 1.00 | FFAR1 (0.76) | FFAR1FFAR4FAAHNFKB1NFKB2 | |
| SCHEMBL25132301 | 1.00 | FFAR1 (0.76) | FFAR1FFAR4FAAHNFKB1NFKB2 | |
| SCHEMBL23092269 | 1.00 | FFAR1 (0.76) | FFAR1FFAR4FAAHNFKB1NFKB2 | |
| SCHEMBL23092271 | 1.00 | FFAR1 (0.76) | FFAR1FFAR4FAAHNFKB1NFKB2 | |
| SCHEMBL23092270 | 1.00 | FFAR1 (0.76) | FFAR1FFAR4FAAHNFKB1NFKB2 | |
| SCHEMBL23092225 | 1.00 | FFAR1 (0.76) | FFAR1FFAR4FAAHNFKB1NFKB2 | |
| SCHEMBL14456195 | 1.00 | FFAR1 (0.76) | FFAR1FFAR4FAAHNFKB1NFKB2 | |
| SCHEMBL14890377 | 1.00 | FFAR1 (0.76) | FFAR1FFAR4FAAHNFKB1NFKB2 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-5491152-A | Derivatives of cyclic ethers and sulfides for the treatment of atherosclerosis | THE DU PONT MERCK PHARMACEUTICAL COMPANY (US) | 1996-02-13 | — | — | US | disclosed |