SCHEMBL9008680

SCHEMBL9008680

C=C(C)C(=O)NC1CC(C)(C)N(C(C)=O)C(C)(C)C1

nearest known ligand 0.33

Predicted protein targets (top 7)

geneUniProtsupporting neighboursconfidence
KDM4E B2RXH2 2/20 0.33
GAA P10253 2/20 0.33
KMT2A Q03164 1/20 0.31
EPHX2 P34913 2/20 0.31
ESR1 P03372 1/20 0.30
LMNA P02545 1/20 0.30
L3MBTL1 Q9Y468 1/20 0.30

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL154350 0.88 KDM4E (0.33) KDM4EGAAKMT2A
SCHEMBL1079185 0.84 MAOB (0.39) KDM4EGAAKMT2A
SCHEMBL107837 0.84 HDAC4 (0.36) KDM4EGAAKMT2A
SCHEMBL7508932 0.84 GAA (0.47) KDM4EGAAKMT2AL3MBTL1
SCHEMBL8589236 0.84 EPHX2 (0.32) KDM4EGAAEPHX2
Hydrochloric Acid SCHEMBL6558029 0.83 GAA (0.49) KDM4EGAAKMT2AL3MBTL1
SCHEMBL8337045 0.81 GAA (0.33) KDM4EGAAKMT2AEPHX2
SCHEMBL9002566 0.81 KDM4E (0.33) KDM4EGAAKMT2AEPHX2LMNA
SCHEMBL345721 0.81 KDM4E (0.33) KDM4EGAAKMT2A
SCHEMBL10578940 0.80 KDM4E (0.32) KDM4EGAAKMT2A

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 3 patents. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
EP-0495130-B1 NOVEL FLUORORESIN AND COATING MATERIAL BASED THEREON ASAHI CHEMICAL IND (JP) 1996-10-30 EP disclosed
US-5283304-A Gloss, hardness, weatherability; room temperature vulcanization ASAHI KASEI KOGYO KABUSHIKI KAISHA (JP) 1994-02-01 US disclosed
EP-0495130-A1 NOVEL FLUORORESIN AND COATING MATERIAL BASED THEREON Asahi Kasei Kogyo Kabushiki Kaisha (JP) 1992-07-22 EP disclosed