Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | P2RY2 | P41231 | 4/20 | 0.57 |
| ▸ | EHMT1 | Q9H9B1 | 1/20 | 0.56 |
| ▸ | P2RY1 | P47900 | 4/20 | 0.53 |
| ▸ | SRC | P12931 | 2/20 | 0.53 |
| ▸ | SMN1; SMN2 | Q16637 | 2/20 | 0.53 |
| ▸ | P2RX1 | P51575 | 1/20 | 0.53 |
| ▸ | P2RX3 | P56373 | 1/20 | 0.53 |
| ▸ | P2RX4 | Q99571 | 1/20 | 0.53 |
| ▸ | P2RX2 | Q9UBL9 | 1/20 | 0.53 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.53 |
| ▸ | DNPH1 | O43598 | 1/20 | 0.52 |
| ▸ | PRKAB2 | O43741 | 1/20 | 0.52 |
| ▸ | TRPM2 | O94759 | 1/20 | 0.52 |
| ▸ | LDHA | P00338 | 1/20 | 0.52 |
| ▸ | ADRB2 | P07550 | 1/20 | 0.52 |
| ▸ | FBP1 | P09467 | 1/20 | 0.52 |
| ▸ | ADORA1 | P30542 | 1/20 | 0.52 |
| ▸ | PRKAG1 | P54619 | 1/20 | 0.52 |
| ▸ | PRKAA2 | P54646 | 1/20 | 0.52 |
| ▸ | PDE4D | Q08499 | 1/20 | 0.52 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL9008963 | 1.00 | P2RY2 (0.57) | P2RY2EHMT1P2RY1SRCSMN1; SMN2 | |
| SCHEMBL8440946 | 0.86 | P2RY2 (0.60) | P2RY2P2RY1SRCSMN1; SMN2P2RX1 | |
| SCHEMBL230821 | 0.85 | EHMT1 (0.63) | P2RY2EHMT1P2RY1SRCSMN1; SMN2 | |
| SCHEMBL8435885 | 0.85 | P2RY2 (0.62) | P2RY2P2RY1SRCSMN1; SMN2P2RX1 | |
| SCHEMBL8441544 | 0.83 | P2RY2 (0.64) | P2RY2P2RY1SRCSMN1; SMN2P2RX1 | |
| SCHEMBL30211841 | 0.83 | P2RY2 (0.59) | P2RY2EHMT1P2RY1SRCSMN1; SMN2 | |
| SCHEMBL29126399 | 0.83 | P2RY2 (0.59) | P2RY2EHMT1P2RY1SRCSMN1; SMN2 | |
| SCHEMBL3164897 | 0.82 | P2RY2 (0.65) | P2RY2P2RY1SRCSMN1; SMN2P2RX1 | |
| SCHEMBL800850 | 0.82 | P2RY2 (0.64) | P2RY2P2RY1SRCSMN1; SMN2P2RX1 | |
| SCHEMBL8438661 | 0.82 | P2RY2 (0.64) | P2RY2P2RY1SRCSMN1; SMN2P2RX1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 4 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-0738274-A1 | NOVEL NUCLEOSIDE-LIPID ADDITION COMPOUNDS, THEIR PRODUCTION AND THEIR PHARMACEUTICAL USE | MAX-DELBRÜCK-CENTRUM FÜR MOLEKULARE MEDIZIN (DE) | 1996-10-23 | — | — | EP | claimed |
| WO-1995018816-A1 | NOVEL NUCLEOSIDE-LIPID ADDITION COMPOUNDS, THEIR PRODUCTION AND THEIR PHARMACEUTICAL USE | Max-Delbrück-Centrum für Molekulare Medizin (DE) | 1995-07-13 | — | — | WO | claimed |
| EP-0738274-A1 | NOVEL NUCLEOSIDE-LIPID ADDITION COMPOUNDS, THEIR PRODUCTION AND THEIR PHARMACEUTICAL USE | MAX-DELBRÜCK-CENTRUM FÜR MOLEKULARE MEDIZIN (DE) | 1996-10-23 | — | — | EP | disclosed |
| WO-1995018816-A1 | NOVEL NUCLEOSIDE-LIPID ADDITION COMPOUNDS, THEIR PRODUCTION AND THEIR PHARMACEUTICAL USE | Max-Delbrück-Centrum für Molekulare Medizin (DE) | 1995-07-13 | — | — | WO | disclosed |