Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | KAT6A | Q92794 | 3/20 | 0.50 |
| ▸ | GRM5 | P41594 | 8/20 | 0.49 |
| ▸ | KAT7 | O95251 | 1/20 | 0.48 |
| ▸ | DRD2 | P14416 | 1/20 | 0.48 |
| ▸ | METAP2 | P50579 | 1/20 | 0.48 |
| ▸ | KAT6B | Q8WYB5 | 1/20 | 0.48 |
| ▸ | KAT5 | Q92993 | 1/20 | 0.48 |
| ▸ | KDM1A | O60341 | 1/20 | 0.48 |
| ▸ | KDM4E | B2RXH2 | 1/20 | 0.45 |
| ▸ | LMNA | P02545 | 1/20 | 0.45 |
| ▸ | CYP1A2 | P05177 | 1/20 | 0.45 |
| ▸ | POLB | P06746 | 1/20 | 0.45 |
| ▸ | CCR1 | P32246 | 1/20 | 0.45 |
| ▸ | CCR5 | P51681 | 1/20 | 0.45 |
| ▸ | CCR8 | P51685 | 1/20 | 0.45 |
| ▸ | METAP1 | P53582 | 1/20 | 0.45 |
| ▸ | BLM | P54132 | 1/20 | 0.45 |
| ▸ | HIF1A | Q16665 | 1/20 | 0.45 |
| ▸ | DOHH | Q9BU89 | 1/20 | 0.45 |
| ▸ | P4HTM | Q9NXG6 | 1/20 | 0.45 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL5945969 | 0.87 | GRM5 (0.56) | KAT6AGRM5KAT7DRD2METAP2 | |
| SCHEMBL5846133 | 0.87 | GRM5 (0.60) | KAT6AGRM5KAT7DRD2METAP2 | |
| SCHEMBL6067871 | 0.87 | KDM4E (0.54) | KDM4ELMNACYP1A2POLBCCR1 | |
| Hydrochloric Acid SCHEMBL6068087 | 0.85 | KDM4E (0.52) | KDM4ELMNACYP1A2POLBCCR1 | |
| SCHEMBL21390791 | 0.80 | EGFR (0.49) | KAT6AKDM4ELMNACYP1A2POLB | |
| SCHEMBL23525598 | 0.79 | PKMYT1 (0.52) | KAT6AGRM5KDM4ELMNACYP1A2 | |
| SCHEMBL22779452 | 0.79 | GRM5 (0.49) | KAT6AGRM5KDM4ELMNACYP1A2 | |
| SCHEMBL30610279 | 0.79 | PKMYT1 (0.52) | KAT6AGRM5KDM4ELMNACYP1A2 | |
| SCHEMBL27433221 | 0.78 | ABL1 (0.50) | KDM4ELMNACYP1A2POLBCCR1 | |
| SCHEMBL18311301 | 0.77 | KAT6A (0.62) | KAT6AGRM5KAT7DRD2METAP2 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-5576338-A | ANTIALLERGENS, ANTIHISTAMINES, ANTIINFLAMMATORY AGENTS AND CYTOPROTECTIVE AGENTS FOR CARDIOVASCULAR DISORDERS | MERCK FROSST CANADA, INC. (CA) | 1996-11-19 | — | — | US | disclosed |