⚠ Novel chemotype — no close known analogue (best Tanimoto < 0.3). Unexplored chemical space relative to ChEMBL.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL7354141 | 0.80 | USP2 (0.46) | — | |
| SCHEMBL6578001 | 0.78 | — | — | |
| SCHEMBL21070916 | 0.77 | TSHR (0.44) | — | |
| SCHEMBL21070639 | 0.77 | TSHR (0.44) | — | |
| SCHEMBL18530451 | 0.77 | TSHR (0.44) | — | |
| SCHEMBL19434532 | 0.77 | TSHR (0.44) | — | |
| SCHEMBL693135 | 0.77 | TSHR (0.43) | — | |
| SCHEMBL3569833 | 0.76 | — | — | |
| SCHEMBL9643006 | 0.76 | — | — | |
| SCHEMBL3569836 | 0.76 | — | — |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 60 patents — showing the first 20. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| CN-118324772-A | Synthesis method and intermediate of furan [3,2-b ] pyridine derivative | 北京颖诺凯胜科技有限公司 | 2024-07-12 | — | — | CN | claimed |
| EP-3752496-A1 | METHODS AND INTERMEDIATES FOR PREPARING A THERAPEUTIC COMPOUND USEFUL IN THE TREATMENT OF RETROVIRIDAE VIRAL INFECTION | GILEAD SCIENCES, INC. (US) | 2020-12-23 | — | — | EP | claimed |
| WO-2019161280-A1 | METHODS AND INTERMEDIATES FOR PREPARING A THERAPEUTIC COMPOUND USEFUL IN THE TREATMENT OF RETROVIRIDAE VIRAL INFECTION | GILEAD SCIENCES, INC. (US) | 2019-08-22 | — | — | WO | claimed |
| WO-2024259171-A2 | KEAP1 INHIBITORS AND USES THEREOF | VIVIDION THERAPEUTICS, INC. (US) | 2024-12-19 | — | — | WO | disclosed |
| CN-111801833-B | Nonaqueous electrolyte and energy device using same | 三菱化学株式会社 | 2024-07-16 | — | — | CN | disclosed |
| CN-118324772-A | Synthesis method and intermediate of furan [3,2-b ] pyridine derivative | 北京颖诺凯胜科技有限公司 | 2024-07-12 | — | — | CN | disclosed |
| US-20240101533-A1 | METHODS AND INTERMEDIATES FOR PREPARING THERAPEUTIC COMPOUNDS | GILEAD SCIENCES, INC. | 2024-03-28 | — | — | US | disclosed |
| EP-4253366-A2 | METHODS AND INTERMEDIATES FOR PREPARING A THERAPEUTIC COMPOUND USEFUL IN THE TREATMENT OF RETROVIRIDAE VIRAL INFECTION | Gilead Sciences, Inc. (US) | 2023-10-04 | — | — | EP | disclosed |
| US-11760746-B2 | Methods and intermediates for preparing therapeutic compounds | GILEAD SCIENCES, INC. (US) | 2023-09-19 | — | — | US | disclosed |
| EP-3752496-B1 | METHODS AND INTERMEDIATES FOR PREPARING A THERAPEUTIC COMPOUND USEFUL IN THE TREATMENT OF RETROVIRIDAE VIRAL INFECTION | GILEAD SCIENCES INC (US) | 2023-07-05 | — | — | EP | disclosed |
| US-20230098076-A1 | A PROCESS FOR PREPARATION OF 3,6-DICHLOROCYANO PYRAZINE, 3,6-DIOXOPIPERAZINE DERIVATIVES AND PRODUCTION OF FAVIPIRAVIR THEREOF | COUNCIL OF SCIENT AND INDUSTRIAL RESEARCH AN INDIAN REGISTERED BODY INCORPORATED UNDER THE REGN (IN) | 2023-03-30 | — | — | US | disclosed |
| WO-1999062893-A2 | NOVEL NEUROKININ ANTAGONISTS, METHOD FOR THE PRODUCTION THEREOF AND PHARMACEUTICAL COMPOSITIONS CONTAINING SAID COMPOUNDS | BOEHRINGER INGELHEIM PHARMA KG (DE) | 1999-12-09 | — | — | WO | disclosed |
| WO-1999021855-A1 | PLEUROMUTILIN DERIVATIVES AS ANTIMICROBIALS | SMITHKLINE BEECHAM P.L.C. (GB) | 1999-05-06 | — | — | WO | disclosed |
| EP-0582790-B1 | Novel method of producing 7-(substituted)-9-[(substituted glycyl)amido]-6-demethyl-6-deoxytetracyclines | AMERICAN CYANAMID CO (US) | 1998-12-23 | — | — | EP | disclosed |
| US-5698735-A | Process for preparing substituted phenylacetic acid derivatives and novel intermediates | BAYER AKTIENGESELLSCHAFT (DE) | 1997-12-16 | — | — | US | disclosed |
| EP-0582790-A1 | Novel method of producing 7-(substituted)-9- (substituted glycyl)amido -6-demethyl-6-deoxytetracyclines | AMERICAN CYANAMID COMPANY (US) | 1994-02-16 | — | — | EP | disclosed |
| US-5284963-A | Reacting 9-amino tetracycline derivative with haloacyl halide in mixture of polar aprotic solvent, inert solvent, base; reacting product under inert atmosphere with nucleophilic amine | AMERICAN CYANAMID COMPANY (US) | 1994-02-08 | — | — | US | disclosed |
| EP-0222413-B1 | NOVEL FORSKOLIN DERIVATIVES | NIPPON KAYAKU KABUSHIKI KAISHA (JP) | 1992-02-05 | — | — | EP | disclosed |
| US-4954642-A | INOTROPIC, HYPOTENSIVE | NIPPON KAYAKU KABUSHIKI KAISHA (JP) | 1990-09-04 | — | — | US | disclosed |
| EP-0222413-A2 | Novel forskolin derivatives | NIPPON KAYAKU KABUSHIKI KAISHA (JP) | 1987-05-20 | — | — | EP | disclosed |