SCHEMBL901035

SCHEMBL901035

N#C/C(=C\c1ccc(O)cc1)c1ccc(O)cc1

nearest known ligand 1.00 ✓ in ChEMBL — recovers established targets

Predicted protein targets (top 20)

geneUniProtsupporting neighboursconfidence
ESR1 P03372 4/20 1.00
ESR2 Q92731 4/20 1.00
NQO2 P16083 2/20 0.76
MEN1 O00255 5/20 0.61
KMT2A Q03164 5/20 0.61
CISD1 Q9NZ45 2/20 0.61
THRB P10828 1/20 0.61
EGFR P00533 2/20 0.56
IGF1R P08069 1/20 0.56
IGF2R P11717 1/20 0.56
ALDH1A1 P00352 6/20 0.53
MAPT P10636 5/20 0.53
RAB9A P51151 4/20 0.53
MAPK1 P28482 3/20 0.53
L3MBTL1 Q9Y468 1/20 0.53
CYP3A4 P08684 2/20 0.52
HPGD P15428 2/20 0.52
KDM4E B2RXH2 2/20 0.52
SLC16A3 O15427 1/20 0.52
SLC16A1 P53985 1/20 0.52

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL901037 1.00 ESR1 (1.00) ESR1ESR2NQO2MEN1KMT2A
SCHEMBL31129163 0.91 ESR1 (0.83) ESR1ESR2NQO2MEN1KMT2A
SCHEMBL16760658 0.91 ESR1 (0.83) ESR1ESR2NQO2MEN1KMT2A
SCHEMBL16760659 0.91 ESR1 (0.83) ESR1ESR2NQO2MEN1KMT2A
SCHEMBL8398204 0.91 ESR1 (0.83) ESR1ESR2NQO2MEN1KMT2A
SCHEMBL9003682 0.91 ESR1 (0.83) ESR1ESR2NQO2MEN1KMT2A
SCHEMBL9003687 0.91 ESR1 (0.83) ESR1ESR2NQO2MEN1KMT2A
SCHEMBL8398202 0.91 ESR1 (0.83) ESR1ESR2NQO2MEN1KMT2A
SCHEMBL6797061 0.90 ESR1 (0.82) ESR1ESR2NQO2MEN1KMT2A
SCHEMBL8088202 0.90 ESR1 (0.82) ESR1ESR2NQO2MEN1KMT2A

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 183 patents — showing the first 20. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
EP-0573573-B1 MESOGENIC GLYCIDYL AMINES DOW CHEMICAL CO (US) 1999-09-29 EP claimed
US-5391651-A Curable mixtures of mesogenic epoxy resins and mesogenic polyamines and cured compositions THE DOW CHEMICAL COMPANY (US) 1995-02-21 US claimed
US-5364912-A Anisotropic melts, reaction of glycidyl ester of dicarboxylic acid and diol or dicarboxylic acid THE DOW CHEMICAL COMPANY (US) 1994-11-15 US claimed
US-5342904-A Polymer modified adducts of epoxy resins and active hydrogen containing compounds containing mesogenic moieties THE DOW CHEMICAL COMPANY (US) 1994-08-30 US claimed
EP-0573573-A1 MESOGENIC GLYCIDYL AMINES THE DOW CHEMICAL COMPANY (US) 1993-12-15 EP claimed
US-5270405-A Mesogenic epoxy compounds THE DOW CHEMICAL COMPANY (US) 1993-12-14 US claimed
US-5270404-A Curable compositions of mesogen-containing advanced epoxy resins and curing agents therefor THE DOW CHEMICAL COMPANY (US) 1993-12-14 US claimed
US-5248740-A Thioepoxides, liquid crystal polymers THE DOW CHEMICAL COMPANY (US) 1993-09-28 US claimed
US-5235008-A Curable THE DOW CHEMICAL COMPANY (US) 1993-08-10 US claimed
US-5218062-A Curable mixtures of mesogenic epoxy resins and mesogenic polyamines and cured compositions THE DOW CHEMICAL COMPANY (US) 1993-06-08 US claimed
US-5182340-A Molding materials having shorter gel time with aliphatic amine curing agents THE DOW CHEMICAL COMPANY (US) 1993-01-26 US claimed
WO-1992015630-A2 MESOGENIC GLYCIDYL AMINES THE DOW CHEMICAL COMPANY (US) 1992-09-17 WO claimed
EP-0475238-A2 Mesogenic glycidyl esters THE DOW CHEMICAL COMPANY (US) 1992-03-18 EP claimed
EP-0473935-A2 Curable mixture of mesogenic epoxy resins and mesogenic polyamines and cured compositions THE DOW CHEMICAL COMPANY (US) 1992-03-11 EP claimed
US-11866584-B2 High-refractive-index composition, high-refractive-index film, and method for manufacturing high-refractive-index film LG CHEM, LTD. (KR) 2024-01-09 US disclosed
US-11111431-B2 Method for reducing the permeability of a subterranean formation to aqueous-based fluids DOW GLOBAL TECHNOLOGIES LLC (US) 2021-09-07 US disclosed
US-20210095128-A1 HIGH-REFRACTIVE-INDEX COMPOSITION, HIGH-REFRACTIVE-INDEX FILM, AND METHOD FOR MANUFACTURING HIGH-REFRACTIVE-INDEX FILM LG CHEM, LTD. (KR) 2021-04-01 US disclosed
EP-0379058-A2 Vinyl ester resins containing mesogenic/rigid rodlike moieties THE DOW CHEMICAL COMPANY (US) 1990-07-25 EP disclosed
EP-0379057-A2 Mesogenic epoxy compounds THE DOW CHEMICAL COMPANY (US) 1990-07-25 EP disclosed
EP-0379055-A2 Mesogenic advanced epoxy compounds THE DOW CHEMICAL COMPANY (US) 1990-07-25 EP disclosed