Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | CDC25A | P30304 | 4/20 | 0.74 |
| ▸ | CDC25B | P30305 | 2/20 | 0.74 |
| ▸ | GPBAR1 | Q8TDU6 | 10/20 | 0.46 |
| ▸ | NR1H4 | Q96RI1 | 5/20 | 0.46 |
| ▸ | AKR1B10 | O60218 | 1/20 | 0.43 |
| ▸ | AKR1B1 | P15121 | 1/20 | 0.43 |
| ▸ | EFNA1 | P20827 | 1/20 | 0.43 |
| ▸ | EPHA2 | P29317 | 1/20 | 0.43 |
| ▸ | PSEN1 | P49768 | 1/20 | 0.43 |
| ▸ | PSEN2 | P49810 | 1/20 | 0.43 |
| ▸ | APH1B | Q8WW43 | 1/20 | 0.43 |
| ▸ | NCSTN | Q92542 | 1/20 | 0.43 |
| ▸ | APH1A | Q96BI3 | 1/20 | 0.43 |
| ▸ | PSENEN | Q9NZ42 | 1/20 | 0.43 |
| ▸ | MEN1 | O00255 | 1/20 | 0.43 |
| ▸ | LMNA | P02545 | 1/20 | 0.43 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.43 |
| ▸ | HSD17B10 | Q99714 | 1/20 | 0.43 |
| ▸ | TDP1 | Q9NUW8 | 1/20 | 0.43 |
| ▸ | MAPT | P10636 | 1/20 | 0.43 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL14446939 | 0.93 | CDC25A (0.78) | CDC25ACDC25BGPBAR1NR1H4 | |
| SCHEMBL9010625 | 0.91 | CDC25A (0.80) | CDC25ACDC25BGPBAR1NR1H4 | |
| SCHEMBL13790310 | 0.88 | CDC25A (0.74) | CDC25ACDC25BGPBAR1NR1H4AKR1B10 | |
| SCHEMBL25893253 | 0.88 | CDC25A (0.74) | CDC25ACDC25BGPBAR1NR1H4AKR1B10 | |
| SCHEMBL818229 | 0.88 | CDC25A (0.69) | CDC25ACDC25BGPBAR1NR1H4AKR1B10 | |
| SCHEMBL823213 | 0.88 | CDC25A (0.69) | CDC25ACDC25BGPBAR1NR1H4AKR1B10 | |
| SCHEMBL4904937 | 0.88 | CDC25A (0.69) | CDC25ACDC25BGPBAR1NR1H4AKR1B10 | |
| SCHEMBL13853983 | 0.88 | CDC25A (0.69) | CDC25ACDC25BGPBAR1NR1H4AKR1B10 | |
| SCHEMBL13790486 | 0.88 | CDC25A (0.69) | CDC25ACDC25BGPBAR1NR1H4AKR1B10 | |
| SCHEMBL817684 | 0.88 | CDC25A (0.69) | CDC25ACDC25BGPBAR1NR1H4AKR1B10 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 4 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-8188064-B2 | Reducing cell differentiation of adipocyte; reducing body fat | WISCONSIN ALUMNI RESEARCH FOUNDATION (US) | 2012-05-29 | — | — | US | disclosed |
| US-8188064-B2 | Reducing cell differentiation of adipocyte; reducing body fat | WISCONSIN ALUMNI RESEARCH FOUNDATION (US) | 2012-05-29 | — | — | US | disclosed |
| US-7541348-B2 | 2-methylene-19-nor-(20S)-1α-hydroxy-trishomopregnacalciferol | WISCONSIN ALUMNI RESEARCH FOUNDATION (US) | 2009-06-02 | — | — | US | disclosed |
| US-7541348-B2 | 2-methylene-19-nor-(20S)-1α-hydroxy-trishomopregnacalciferol | WISCONSIN ALUMNI RESEARCH FOUNDATION (US) | 2009-06-02 | — | — | US | disclosed |