Trifluoroacetic Acid

Trifluoroacetic Acid

SCHEMBL901073

CN(CCCCC(=O)Nc1ccc(CNCC(O)c2ccc(O)c3[nH]c(=O)ccc23)cc1)C(=O)CCN1CCC(OC(=O)Nc2ccccc2-c2ccccc2)CC1.O=C(O)C(F)(F)F.O=C(O)C(F)(F)F

nearest known ligand 0.94

Full drug profile on Sugi Atlas →

Predicted protein targets (top 2)

geneUniProtsupporting neighboursconfidence
CHRM3 P20309 20/20 0.94
ADRB2 P07550 18/20 0.94

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
Trifluoroacetic Acid SCHEMBL694506 1.00 CHRM3 (0.94) CHRM3ADRB2
Trifluoroacetic Acid SCHEMBL693877 0.99 CHRM3 (0.94) CHRM3ADRB2
SCHEMBL890834 0.97 CHRM3 (1.00) CHRM3ADRB2
SCHEMBL730346 0.97 CHRM3 (1.00) CHRM3ADRB2
SCHEMBL730345 0.97 CHRM3 (1.00) CHRM3ADRB2
Fluoride SCHEMBL890954 0.96 CHRM3 (0.99) CHRM3ADRB2
SCHEMBL741158 0.96 CHRM3 (1.00) CHRM3ADRB2
Oxalic Acid SCHEMBL890700 0.95 CHRM3 (0.97) CHRM3ADRB2
Oxalic Acid SCHEMBL890698 0.95 CHRM3 (0.97) CHRM3ADRB2
Trifluoroacetic Acid SCHEMBL14988954 0.95 CHRM3 (0.94) CHRM3ADRB2

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
EP-2621917-A1 CRYSTALLINE OXALATE SALTS OF A DIAMIDE COMPOUND Theravance, Inc. (US) 2013-08-07 EP disclosed
WO-2012044825-A1 CRYSTALLINE OXALATE SALTS OF A DIAMIDE COMPOUND THERAVANCE, INC. (US) 2012-04-05 WO disclosed