SCHEMBL9010833

SCHEMBL9010833

[NH]c1nc2ncnc(O)c2[nH]1

nearest known ligand 0.35

Predicted protein targets (top 7)

geneUniProtsupporting neighboursconfidence
ADORA2A P29274 1/20 0.35
ADORA1 P30542 1/20 0.35
NUDT1 P36639 2/20 0.33
PI4KA P42356 1/20 0.31
PI4K2B Q8TCG2 1/20 0.31
PI4K2A Q9BTU6 1/20 0.31
PI4KB Q9UBF8 1/20 0.31

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL2639251 0.79 ADORA2A (0.37) ADORA2AADORA1NUDT1PI4KAPI4K2B
SCHEMBL8906323 0.78 AKT2 (0.44) ADORA2AADORA1NUDT1PI4KAPI4K2B
SCHEMBL94915 0.76 ADORA2A (0.35) ADORA2AADORA1NUDT1PI4KAPI4K2B
SCHEMBL5667619 0.76 ADORA2A (0.43) ADORA2AADORA1NUDT1PI4KAPI4K2B
SCHEMBL612166 0.76 ADORA2A (0.35) ADORA2AADORA1NUDT1PI4KAPI4K2B
SCHEMBL931970 0.76 ADORA2A (0.61) ADORA2AADORA1NUDT1PI4KAPI4K2B
SCHEMBL16513158 0.76 ADORA2A (0.35) ADORA2AADORA1NUDT1PI4KAPI4K2B
SCHEMBL7168415 0.76 ADORA2A (0.35) ADORA2AADORA1NUDT1PI4KAPI4K2B
SCHEMBL932299 0.76 ADORA2A (0.35) ADORA2AADORA1NUDT1PI4KAPI4K2B
Water SCHEMBL3986355 0.74 ADORA2A (0.34) ADORA2AADORA1NUDT1PI4KAPI4K2B

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 46 patents — showing the first 20. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
US-20220003771-A1 METHODS OF DETECTING A POLYPEPTIDE HAVING ANAPLASTIC LYMPHOMA KINASE ACTIVITY IN KIDNEY CANCER CELL SIGNALING TECHNOLOGY, INC. (US) 2022-01-06 US disclosed
CN-110520443-A FGF21 analog antibody and application thereof NOVARTIS AG 2019-11-29 CN disclosed
CN-110133251-A Purify aflatoxin-cyclopiazonic acid immunosorbent and immune affinity column 中国农业科学院油料作物研究所 2019-08-16 CN disclosed
CN-110133250-A Purify aflatoxin, sterigmatocystin, cyclopiazonic acid immunosorbent and compound affinity column 中国农业科学院油料作物研究所 2019-08-16 CN disclosed
CN-110133249-A Purify aflatoxin, cyclopiazonic acid, ochratoxin A and zearalenone immunosorbent and immune affinity column 中国农业科学院油料作物研究所 2019-08-16 CN disclosed
CN-106932370-B The synchronous chromatography time-resolved fluorescence kit for detecting five kinds of mycotoxins and application 中国农业科学院油料作物研究所 2019-08-13 CN disclosed
CN-106977600-B Purify fumonisin B1, aflatoxin, ochratoxin A, zearalenone immunosorbent and compound affinity column 中国农业科学院油料作物研究所 2019-08-13 CN disclosed
CN-110108873-A The synchronous time-resolved fluorescence kit for detecting aflatoxin, cyclopiazonic acid, ochratoxin A and zearalenone 中国农业科学院油料作物研究所 2019-08-09 CN disclosed
CN-110108874-A Quickly colloid gold immune analysis test paper item, preparation and its application of detection cyclopiazonic acid 中国农业科学院油料作物研究所 2019-08-09 CN disclosed
CN-110108875-A The synchronous immuno-chromatographic test paper strip for detecting aflatoxin, cyclopiazonic acid, ochratoxin A and zearalenone 中国农业科学院油料作物研究所 2019-08-09 CN disclosed
EP-0354808-A2 Polypeptide-induced monoclonal receptors to protein ligands PROGENX, INC. (US) 1990-02-14 EP disclosed
WO-1988008135-A1 HUMAN MONOCLONAL ANTIBODIES BINDING DETERMINANTS OF GRAM NEGATIVE BACTERIA XOMA CORPORATION (US) 1988-10-20 WO disclosed
EP-0232871-A2 Human monoclonal antibody, hybridoma producing the same and its use Yoshitomi Pharmaceutical Industries, Ltd. (JP) 1987-08-19 EP disclosed
US-4675295-A Process for producing subculturable lymphokine-producing human T cell hybridomas DENKI KAGAKU KOGYO KABUSHIKI KAISHA (JP) 1987-06-23 US disclosed
EP-0152477-A4 POLYPEPTIDE-INDUCED MONOCLONAL ANTIBODIES TO ONCOPROTEINS. SCRIPPS CLINIC RES (US) 1987-04-16 EP disclosed
WO-1985004653-A1 ANTIBODIES TO HUMAN INTERLEUKIN-2 INDUCED BY SYNTHETIC POLYPEPTIDES SCRIPPS CLINIC AND RESEARCH FOUNDATION (US) 1985-10-24 WO disclosed
EP-0060871-B1 MONOCLONAL ANTIBODIES SPECIFIC FOR HUMAN HEMATOPOIETIC CELL SURFACE GLYCOPROTEINS THE SALK INSTITUTE FOR BIOLOGICAL STUDIES (US) 1985-10-23 EP disclosed
EP-0157643-A2 Antibodies to human interleukin-2 induced by synthetic polypeptides SCRIPPS CLINIC AND RESEARCH FOUNDATION (US) 1985-10-09 EP disclosed
EP-0152477-A1 POLYPEPTIDE-INDUCED MONOCLONAL ANTIBODIES TO ONCOPROTEINS. SCRIPPS CLINIC RES (US) 1985-08-28 EP disclosed
WO-1985000807-A1 POLYPEPTIDE-INDUCED MONOCLONAL ANTIBODIES TO ONCOPROTEINS SCRIPPS CLINIC AND RESEARCH FOUNDATION (US) 1985-02-28 WO disclosed