Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | CYP1A1 | P04798 | 2/20 | 0.41 |
| ▸ | CYP1A2 | P05177 | 2/20 | 0.41 |
| ▸ | CYP1B1 | Q16678 | 2/20 | 0.41 |
| ▸ | ALDH1A1 | P00352 | 5/20 | 0.39 |
| ▸ | CYP3A4 | P08684 | 1/20 | 0.39 |
| ▸ | TSHR | P16473 | 1/20 | 0.39 |
| ▸ | PLK1 | P53350 | 1/20 | 0.38 |
| ▸ | MEN1 | O00255 | 2/20 | 0.36 |
| ▸ | KMT2A | Q03164 | 2/20 | 0.36 |
| ▸ | MAPT | P10636 | 5/20 | 0.35 |
| ▸ | NPSR1 | Q6W5P4 | 2/20 | 0.35 |
| ▸ | LMNA | P02545 | 2/20 | 0.34 |
| ▸ | SLC6A4 | P31645 | 2/20 | 0.34 |
| ▸ | ALOX15 | P16050 | 1/20 | 0.34 |
| ▸ | SLC6A2 | P23975 | 1/20 | 0.34 |
| ▸ | SLC6A3 | Q01959 | 1/20 | 0.34 |
| ▸ | HTT | P42858 | 1/20 | 0.34 |
| ▸ | MAOB | P27338 | 1/20 | 0.33 |
| ▸ | AOC3 | Q16853 | 1/20 | 0.33 |
| ▸ | HTR2A | P28223 | 1/20 | 0.33 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL11464966 | 0.83 | CYP3A4 (0.58) | CYP1A1CYP1A2CYP1B1ALDH1A1CYP3A4 | |
| SCHEMBL10015246 | 0.82 | MEN1 (0.48) | CYP3A4TSHRMEN1KMT2ASMN1; SMN2 | |
| SCHEMBL11109918 | 0.79 | SRC (0.54) | CYP1A1CYP1A2CYP1B1ALDH1A1CYP3A4 | |
| SCHEMBL5933784 | 0.78 | CYP3A4 (0.47) | CYP1A1CYP1A2CYP1B1ALDH1A1CYP3A4 | |
| Potassium Ion SCHEMBL11777485 | 0.76 | CYP1A1 (0.39) | CYP1A1CYP1A2CYP1B1ALDH1A1CYP3A4 | |
| SCHEMBL3756382 | 0.76 | TSHR (0.67) | ALDH1A1CYP3A4TSHRMEN1KMT2A | |
| SCHEMBL643849 | 0.76 | CA1 (0.52) | ALDH1A1CYP3A4TSHRPLK1LMNA | |
| SCHEMBL11766120 | 0.73 | CYP3A4 (0.42) | CYP1A1CYP1A2CYP1B1ALDH1A1CYP3A4 | |
| SCHEMBL561706 | 0.73 | MEN1 (0.64) | CYP1A2ALDH1A1CYP3A4TSHRMEN1 | |
| SCHEMBL1809191 | 0.71 | CYP1A2 (0.47) | CYP1A2CYP3A4TSHRMEN1KMT2A |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 4 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-5585364-A | SIDE EFFECT REDUCTION WHEN ADMINISTERED TO TREAT THE AIDS VIRUS | BRITISH TECHNOLOGY GROUP LIMITED (GB) | 1996-12-17 | — | — | US | disclosed |
| EP-0392791-B1 | Antiviral compounds | BRITISH TECH GROUP (GB) | 1995-08-02 | — | — | EP | disclosed |
| WO-1990012023-A1 | ANTIVIRAL COMPOUNDS | WALKER RICHARD THOMAS (GB) | 1990-10-18 | — | — | WO | disclosed |
| EP-0392791-A1 | Antiviral compounds | BTG INTERNATIONAL LIMITED (GB) | 1990-10-17 | — | — | EP | disclosed |