Predicted protein targets (top 8)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | LMNA | P02545 | 6/20 | 0.39 |
| ▸ | MAPT | P10636 | 3/20 | 0.39 |
| ▸ | SMN1; SMN2 | Q16637 | 3/20 | 0.38 |
| ▸ | MAPK1 | P28482 | 1/20 | 0.38 |
| ▸ | KDM4E | B2RXH2 | 1/20 | 0.37 |
| ▸ | GAA | P10253 | 1/20 | 0.36 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.36 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.36 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL900583 | 0.88 | DRD3 (0.36) | LMNAMAPK1KMT2AALDH1A1 | |
| SCHEMBL12474382 | 0.88 | DRD3 (0.36) | LMNAMAPK1KMT2AALDH1A1 | |
| SCHEMBL12474403 | 0.87 | DRD3 (0.35) | LMNAMAPK1KMT2AALDH1A1 | |
| SCHEMBL2720604 | 0.87 | DRD3 (0.37) | LMNASMN1; SMN2MAPK1 | |
| Hydrochloric Acid SCHEMBL2721847 | 0.86 | MAPK1 (0.38) | LMNASMN1; SMN2MAPK1 | |
| SCHEMBL2720193 | 0.85 | DRD3 (0.42) | LMNAMAPTMAPK1KMT2AALDH1A1 | |
| SCHEMBL900530 | 0.85 | TSHR (0.38) | LMNASMN1; SMN2MAPK1ALDH1A1 | |
| SCHEMBL2721762 | 0.85 | DRD3 (0.41) | LMNASMN1; SMN2MAPK1KMT2AALDH1A1 | |
| SCHEMBL900461 | 0.85 | DRD3 (0.44) | LMNASMN1; SMN2MAPK1 | |
| SCHEMBL2721698 | 0.84 | DRD3 (0.40) | LMNAMAPTMAPK1KMT2AALDH1A1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-2621916-A1 | BENZAZOLE DERIVATIVES AS HISTAMINE H4 RECEPTOR LIGANDS | BIOPROJET (FR) | 2013-08-07 | — | — | EP | disclosed |
| WO-2012041860-A1 | BENZAZOLE DERIVATIVES AS HISTAMINE H4 RECEPTOR LIGANDS | BIOPROJET (FR) | 2012-04-05 | — | — | WO | disclosed |