Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | MMP2 | P08253 | 2/20 | 0.40 |
| ▸ | MMP12 | P39900 | 2/20 | 0.40 |
| ▸ | MMP9 | P14780 | 1/20 | 0.40 |
| ▸ | KCNH2 | Q12809 | 4/20 | 0.39 |
| ▸ | APP | P05067 | 1/20 | 0.38 |
| ▸ | FFAR1 | O14842 | 1/20 | 0.37 |
| ▸ | FFAR4 | Q5NUL3 | 1/20 | 0.37 |
| ▸ | NAAA | Q02083 | 1/20 | 0.37 |
| ▸ | NPC1 | O15118 | 2/20 | 0.36 |
| ▸ | RAB9A | P51151 | 2/20 | 0.36 |
| ▸ | SMN1; SMN2 | Q16637 | 2/20 | 0.36 |
| ▸ | LIPG | Q9Y5X9 | 1/20 | 0.36 |
| ▸ | NPSR1 | Q6W5P4 | 1/20 | 0.36 |
| ▸ | KDM4E | B2RXH2 | 1/20 | 0.36 |
| ▸ | MEN1 | O00255 | 1/20 | 0.36 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.36 |
| ▸ | TP53 | P04637 | 1/20 | 0.36 |
| ▸ | CYP1A2 | P05177 | 1/20 | 0.36 |
| ▸ | CYP3A4 | P08684 | 1/20 | 0.36 |
| ▸ | CYP2D6 | P10635 | 1/20 | 0.36 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL31470816 | 0.93 | APP (0.41) | MMP2MMP12MMP9APPFFAR1 | |
| SCHEMBL6252045 | 0.77 | APP (0.48) | KCNH2APPNPC1RAB9ASMN1; SMN2 | |
| SCHEMBL9015870 | 0.76 | FFAR1 (0.58) | MMP2MMP12KCNH2FFAR1FFAR4 | |
| SCHEMBL4071200 | 0.76 | FFAR1 (0.58) | MMP2MMP12KCNH2FFAR1FFAR4 | |
| SCHEMBL4073903 | 0.76 | FFAR1 (0.58) | MMP2MMP12KCNH2FFAR1FFAR4 | |
| SCHEMBL7139040 | 0.76 | FFAR1 (0.58) | MMP2MMP12KCNH2FFAR1FFAR4 | |
| SCHEMBL2027461 | 0.76 | FFAR1 (0.58) | MMP2MMP12KCNH2FFAR1FFAR4 | |
| SCHEMBL2350387 | 0.76 | FFAR1 (0.58) | MMP2MMP12KCNH2FFAR1FFAR4 | |
| SCHEMBL5314931 | 0.73 | FFAR1 (0.55) | MMP2MMP12KCNH2APPFFAR1 | |
| SCHEMBL2837648 | 0.73 | FFAR1 (0.57) | KCNH2FFAR1FFAR4LIPGKDM4E |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-5498736-A | 2,5-reactive substituent group-containing siloles, silole polycondensates and preparation thereof | SHIN-ETSU CHEMICAL CO., LTD. (JP) | 1996-03-12 | — | — | US | disclosed |