Predicted protein targets (top 17)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | ABL1 | P00519 | 1/20 | 0.53 |
| ▸ | KCNH3 | Q9ULD8 | 2/20 | 0.46 |
| ▸ | EPHX1 | P07099 | 1/20 | 0.44 |
| ▸ | PRSS1 | P07477 | 6/20 | 0.44 |
| ▸ | F2 | P00734 | 2/20 | 0.44 |
| ▸ | PRSS2 | P07478 | 2/20 | 0.44 |
| ▸ | PRSS3 | P35030 | 2/20 | 0.44 |
| ▸ | TMPRSS6 | Q8IU80 | 2/20 | 0.44 |
| ▸ | ST14 | Q9Y5Y6 | 2/20 | 0.44 |
| ▸ | PLK1 | P53350 | 3/20 | 0.42 |
| ▸ | MAPT | P10636 | 2/20 | 0.41 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.41 |
| ▸ | ADRA2A | P08913 | 1/20 | 0.39 |
| ▸ | S1PR2 | O95136 | 1/20 | 0.39 |
| ▸ | LMNA | P02545 | 1/20 | 0.39 |
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.39 |
| ▸ | NPSR1 | Q6W5P4 | 1/20 | 0.39 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL28861449 | 0.98 | ABL1 (0.50) | ABL1KCNH3EPHX1PRSS1F2 | |
| SCHEMBL187892 | 0.91 | ABL1 (0.59) | ABL1KCNH3EPHX1PRSS1F2 | |
| SCHEMBL16439908 | 0.91 | ABL1 (0.59) | ABL1KCNH3EPHX1PRSS1F2 | |
| SCHEMBL30220137 | 0.91 | ABL1 (0.59) | ABL1KCNH3EPHX1PRSS1F2 | |
| SCHEMBL2720066 | 0.91 | ABL1 (0.59) | ABL1KCNH3EPHX1PRSS1F2 | |
| SCHEMBL9506930 | 0.91 | ABL1 (0.59) | ABL1KCNH3EPHX1PRSS1F2 | |
| SCHEMBL3395174 | 0.91 | ABL1 (0.59) | ABL1KCNH3EPHX1PRSS1F2 | |
| SCHEMBL11498100 | 0.91 | ABL1 (0.59) | ABL1KCNH3EPHX1PRSS1F2 | |
| SCHEMBL11476522 | 0.91 | ABL1 (0.59) | ABL1KCNH3EPHX1PRSS1F2 | |
| SCHEMBL17056824 | 0.91 | ABL1 (0.59) | ABL1KCNH3EPHX1PRSS1F2 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-5510224-A | HYDROPHOBIC SENSITIZER | SEIKO INSTRUMENTS INC. (JP) | 1996-04-23 | — | — | US | disclosed |
| US-5292458-A | Containing polymerizable monomer and initiator | SEIKO INSTRUMENTS INC. (JP) | 1994-03-08 | — | — | US | disclosed |