Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | TSHR | P16473 | 4/20 | 0.70 |
| ▸ | ABCC4 | O15439 | 1/20 | 0.55 |
| ▸ | MAPT | P10636 | 1/20 | 0.55 |
| ▸ | ALDH1A1 | P00352 | 4/20 | 0.50 |
| ▸ | GAA | P10253 | 1/20 | 0.50 |
| ▸ | LMNA | P02545 | 3/20 | 0.48 |
| ▸ | NFKB1 | P19838 | 1/20 | 0.48 |
| ▸ | PMP22 | Q01453 | 1/20 | 0.48 |
| ▸ | EPHX2 | P34913 | 1/20 | 0.47 |
| ▸ | PKM | P14618 | 1/20 | 0.45 |
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.45 |
| ▸ | PAM | P19021 | 2/20 | 0.44 |
| ▸ | GPR84 | Q9NQS5 | 3/20 | 0.41 |
| ▸ | FFAR1 | O14842 | 1/20 | 0.41 |
| ▸ | FFAR4 | Q5NUL3 | 1/20 | 0.41 |
| ▸ | PPARG | P37231 | 2/20 | 0.40 |
| ▸ | PPARD | Q03181 | 2/20 | 0.40 |
| ▸ | PPARA | Q07869 | 2/20 | 0.40 |
| ▸ | SLC22A6 | Q4U2R8 | 1/20 | 0.40 |
| ▸ | SLC22A8 | Q8TCC7 | 1/20 | 0.40 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL530482 | 1.00 | TSHR (0.70) | TSHRABCC4MAPTALDH1A1GAA | |
| SCHEMBL14533033 | 1.00 | TSHR (0.70) | TSHRABCC4MAPTALDH1A1GAA | |
| SCHEMBL2249400 | 1.00 | TSHR (0.70) | TSHRABCC4MAPTALDH1A1GAA | |
| SCHEMBL11763281 | 1.00 | TSHR (0.70) | TSHRABCC4MAPTALDH1A1GAA | |
| SCHEMBL87404 | 0.98 | TSHR (0.67) | TSHRABCC4MAPTALDH1A1GAA | |
| Ethylene SCHEMBL28109697 | 0.96 | TSHR (0.65) | TSHRABCC4MAPTALDH1A1GAA | |
| SCHEMBL2824126 | 0.94 | TSHR (0.61) | TSHRABCC4MAPTALDH1A1GAA | |
| SCHEMBL180289 | 0.92 | TSHR (0.81) | TSHRABCC4MAPTALDH1A1GAA | |
| SCHEMBL11795597 | 0.92 | TSHR (0.81) | TSHRABCC4MAPTALDH1A1GAA | |
| SCHEMBL5392962 | 0.92 | TSHR (0.81) | TSHRABCC4MAPTALDH1A1GAA |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-0494169-B1 | Process for the preparation of charged thermosetting polyurethane compositions and homogeneous and stable suspensions of the charge | JAYMO S N C (FR) | 1996-11-13 | — | — | EP | claimed |