SCHEMBL901146

SCHEMBL901146

CC(=O)OC1C2(C)CCC(C2)C1(C)C.CC(=O)OC1C2(C)CCC(C2)C1(C)C

nearest known ligand 0.55

Predicted protein targets (top 20)

geneUniProtsupporting neighboursconfidence
CYP3A4 P08684 2/20 0.55
CYP2D6 P10635 1/20 0.55
CYP2C9 P11712 1/20 0.55
CYP2C19 P33261 1/20 0.55
TDP1 Q9NUW8 1/20 0.55
GPR84 Q9NQS5 1/20 0.51
CTSV O60911 1/20 0.38
CTSL P07711 1/20 0.38
CTSB P07858 1/20 0.38
CTSS P25774 1/20 0.38
CTSK P43235 1/20 0.38
ACHE P22303 1/20 0.38
SCN9A Q15858 1/20 0.37
TAS1R3 Q7RTX0 2/20 0.37
TAS1R1 Q7RTX1 1/20 0.37
TAS1R2 Q8TE23 1/20 0.35
ALOX15 P16050 1/20 0.33
APP P05067 4/20 0.33
ALDH1A1 P00352 1/20 0.33
LMNA P02545 1/20 0.33

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL891396 1.00 CYP3A4 (0.55) CYP3A4CYP2D6CYP2C9CYP2C19TDP1
SCHEMBL18076323 1.00 CYP3A4 (0.55) CYP3A4CYP2D6CYP2C9CYP2C19TDP1
SCHEMBL184488 1.00 CYP3A4 (0.55) CYP3A4CYP2D6CYP2C9CYP2C19TDP1
SCHEMBL14867336 1.00 CYP3A4 (0.55) CYP3A4CYP2D6CYP2C9CYP2C19TDP1
Acetic Acid SCHEMBL17748827 0.96 CYP3A4 (0.56) CYP3A4CYP2D6CYP2C9CYP2C19TDP1
SCHEMBL25383430 0.87 CYP3A4 (0.56) CYP3A4CYP2D6CYP2C9CYP2C19TDP1
SCHEMBL20722267 0.87 CYP3A4 (0.56) CYP3A4CYP2D6CYP2C9CYP2C19TDP1
SCHEMBL20722270 0.85 CYP3A4 (0.58) CYP3A4CYP2D6CYP2C9CYP2C19TDP1
SCHEMBL10660858 0.85 CYP3A4 (0.58) CYP3A4CYP2D6CYP2C9CYP2C19TDP1
SCHEMBL17338713 0.83 CYP3A4 (0.43) CYP3A4CYP2D6CYP2C9CYP2C19TDP1

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 5 patents. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
US-11062794-B2 Olfactory signature and odorant mixture having the same YEDA RESEARCH AND DEVELOPMENT CO. LTD. (IL) 2021-07-13 US disclosed
US-20180253534-A1 OLFACTORY SIGNATURE AND ODORANT MIXTURE HAVING THE SAME YEDA RESEARCH AND DEVELOPMENT CO. LTD. (IL) 2018-09-06 US disclosed
EP-2621462-A1 ORAL CARE COMPOSITIONS WITH IMPROVED FLAVOR The Procter and Gamble Company (US) 2013-08-07 EP disclosed
WO-2013035070-A1 OLFACTORY SIGNATURE AND ODORANT MIXTURE HAVING THE SAME YEDA RESEARCH AND DEVELOPMENT CO. LTD. (IL) 2013-03-14 WO disclosed
WO-2012044728-A1 ORAL CARE COMPOSITIONS WITH IMPROVED FLAVOR THE PROCTER & GAMBLE COMPANY (US) 2012-04-05 WO disclosed