Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | KDM4E | B2RXH2 | 5/20 | 0.66 |
| ▸ | GAA | P10253 | 2/20 | 0.66 |
| ▸ | ALDH1A1 | P00352 | 2/20 | 0.66 |
| ▸ | NR4A1 | P22736 | 1/20 | 0.63 |
| ▸ | NR4A2 | P43354 | 1/20 | 0.63 |
| ▸ | NR4A3 | Q92570 | 1/20 | 0.63 |
| ▸ | POLB | P06746 | 1/20 | 0.59 |
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.59 |
| ▸ | MMP3 | P08254 | 1/20 | 0.57 |
| ▸ | HDAC8 | Q9BY41 | 1/20 | 0.57 |
| ▸ | PTPN1 | P18031 | 1/20 | 0.55 |
| ▸ | CDC25B | P30305 | 1/20 | 0.55 |
| ▸ | PLK1 | P53350 | 1/20 | 0.55 |
| ▸ | KMT2A | Q03164 | 3/20 | 0.54 |
| ▸ | MEN1 | O00255 | 1/20 | 0.54 |
| ▸ | ATM | Q13315 | 1/20 | 0.52 |
| ▸ | HPGD | P15428 | 2/20 | 0.50 |
| ▸ | MAPT | P10636 | 1/20 | 0.50 |
| ▸ | TSHR | P16473 | 1/20 | 0.50 |
| ▸ | HSD17B10 | Q99714 | 1/20 | 0.50 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL43084 | 0.98 | KDM4E (0.68) | KDM4EGAAALDH1A1NR4A1NR4A2 | |
| SCHEMBL29381201 | 0.98 | KDM4E (0.68) | KDM4EGAAALDH1A1NR4A1NR4A2 | |
| SCHEMBL14837757 | 0.96 | KDM4E (0.66) | KDM4EGAAALDH1A1NR4A1NR4A2 | |
| SCHEMBL29070800 | 0.96 | KDM4E (0.66) | KDM4EGAAALDH1A1NR4A1NR4A2 | |
| Potassium SCHEMBL29689182 | 0.96 | KDM4E (0.66) | KDM4EGAAALDH1A1NR4A1NR4A2 | |
| SCHEMBL18859030 | 0.96 | KDM4E (0.66) | KDM4EGAAALDH1A1NR4A1NR4A2 | |
| Hydrochloric Acid SCHEMBL3149083 | 0.96 | KDM4E (0.66) | KDM4EGAAALDH1A1NR4A1NR4A2 | |
| SCHEMBL18859029 | 0.96 | KDM4E (0.66) | KDM4EGAAALDH1A1NR4A1NR4A2 | |
| Hydrochloric Acid SCHEMBL29605461 | 0.96 | KDM4E (0.66) | KDM4EGAAALDH1A1NR4A1NR4A2 | |
| Ammonia Solution, Strong SCHEMBL1553414 | 0.96 | KDM4E (0.66) | KDM4EGAAALDH1A1NR4A1NR4A2 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-5498736-A | 2,5-reactive substituent group-containing siloles, silole polycondensates and preparation thereof | SHIN-ETSU CHEMICAL CO., LTD. (JP) | 1996-03-12 | — | — | US | disclosed |