SCHEMBL901171

SCHEMBL901171

NC(=O)C[C@H](NC(=O)CNC(=O)[C@H](CC(N)=O)NC(=O)[C@@H](N)CC(N)=O)C(=O)NCC(=O)O

nearest known ligand 0.47

Predicted protein targets (top 17)

geneUniProtsupporting neighboursconfidence
PTGS1 P23219 1/20 0.47
GSTK1 Q9Y2Q3 1/20 0.47
GLO1 Q04760 2/20 0.41
ECE1 P42892 3/20 0.37
OPRD1 P41143 5/20 0.35
OPRM1 P35372 4/20 0.35
OPRK1 P41145 1/20 0.35
MEN1 O00255 1/20 0.35
KMT2A Q03164 1/20 0.35
PDCD1LG2 Q9BQ51 1/20 0.34
CD274 Q9NZQ7 1/20 0.34
MMP8 P22894 1/20 0.34
MDM4 O15151 1/20 0.34
ITGB3 P05106 1/20 0.34
ITGB1 P05556 1/20 0.34
ITGAV P06756 1/20 0.34
ITGA5 P08648 1/20 0.34

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL1409212 0.99 PTGS1 (0.46) PTGS1GSTK1GLO1ECE1OPRD1
SCHEMBL8431345 0.97 PTGS1 (0.45) PTGS1GSTK1GLO1ECE1OPRD1
SCHEMBL8135287 0.97 PTGS1 (0.45) PTGS1GSTK1GLO1ECE1OPRD1
SCHEMBL9225749 0.96 PTGS1 (0.44) PTGS1GSTK1GLO1ECE1OPRD1
SCHEMBL17479582 0.96 PTGS1 (0.46) PTGS1GSTK1GLO1ECE1OPRD1
SCHEMBL1443581 0.96 PTGS1 (0.46) PTGS1GSTK1GLO1ECE1OPRD1
SCHEMBL8503980 0.96 PTGS1 (0.46) PTGS1GSTK1GLO1ECE1OPRD1
SCHEMBL17479694 0.95 PTGS1 (0.48) PTGS1GSTK1GLO1MEN1KMT2A
SCHEMBL153301 0.95 PTGS1 (0.48) PTGS1GSTK1GLO1MEN1KMT2A
SCHEMBL8045766 0.94 PTGS1 (0.44) PTGS1GSTK1GLO1ECE1PDCD1LG2

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 182 patents — showing the first 20. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
CN-111770996-B Mutant beta-glucosidase 花王株式会社 2024-03-26 CN disclosed
CN-113956327-B Polypeptide targeting human APC protein and application thereof in preparation of medicines 中山大学肿瘤防治中心 2024-01-30 CN disclosed
WO-2023219160-A1 NOVEL CELLULAR IMMUNE-POTENTIATING ADJUVANT 日本ビーシージー製造株式会社 2023-11-16 WO disclosed
CN-111757939-B Mutant beta-glucosidase 花王株式会社 2023-11-07 CN disclosed
CN-116802197-A Pharmaceutical composition for preventing or treating tuberculosis 格纳西尼有限公司 2023-09-22 CN disclosed
CN-115989412-A Rapid and simple antibody detection using covalently immobilized self-assembled polypeptides 西西欧艾(杭州)生物医药有限责任公司 2023-04-18 CN disclosed
CN-115956090-A Immobilized self-assembling protein multimers 西西欧艾(杭州)生物医药有限责任公司 2023-04-11 CN disclosed
CN-108350475-B Steviol glycoside using AOBGL1 homologue and method for producing steviol 三得利控股株式会社 2022-12-13 CN disclosed
CN-115279789-A Antibodies that disrupt the interaction of GAL3 and insulin receptor or integrin and methods of use thereof 真和制药有限公司 2022-11-01 CN disclosed
CN-108138198-B Microorganisms engineered for improved yield 合成基因组股份有限公司 2022-10-28 CN disclosed
WO-1998005347-A1 COMPOUNDS THAT INHIBIT INTERACTION BETWEEN SIGNAL-TRANSDUCING PROTEINS AND THE GLGF (PDZ/DHR) DOMAIN AND USES THEREOF THE TRUSTEES OF COLUMBIA UNIVERSITY IN THE CITY OF NEW YORK (US) 1998-02-12 WO disclosed
EP-0822980-A1 RECOMBINANT INFECTIOUS LARYNGOTRACHEITIS VIRUS AND USES THEREOF SYNTRO CORPORATION (US) 1998-02-11 EP disclosed
WO-1998004702-A2 PROTEINS, IN PARTICULAR MEMBRANE PROTEINS, OF HELICOBACTER PYLORI, THEIR PREPARATION AND USE CHIRON BEHRING GMBH & CO. (DE) 1998-02-05 WO disclosed
WO-1997009428-A9 COMPOUNDS AND METHODS FOR IMMUNOTHERAPY AND DIAGNOSIS OF TUBERCULOSIS 1997-05-15 WO disclosed
WO-1997009429-A2 COMPOUNDS AND METHODS FOR DIAGNOSIS OF TUBERCULOSIS CORIXA CORPORATION (US) 1997-03-13 WO disclosed
WO-1996029396-A1 RECOMBINANT INFECTIOUS LARYNGOTRACHEITIS VIRUS AND USES THEREOF SYNTRO CORPORATION (US) 1996-09-26 WO disclosed
EP-0663010-A1 METHODS FOR INCREASING SECRETION OF OVEREXPRESSED PROTEINS RESEARCH CORPORATION TECHNOLOGIES, INC. (US) 1995-07-19 EP disclosed
WO-1994008012-A1 METHODS FOR INCREASING SECRETION OF OVEREXPRESSED PROTEINS RESEARCH CORPORATION TECHNOLOGIES, INC. (US) 1994-04-14 WO disclosed
EP-0569527-A1 INHERITED AND SOMATIC MUTATIONS OF APC GENE IN COLORECTAL CANCER OF HUMANS THE JOHNS HOPKINS UNIVERSITY (US) 1993-11-18 EP disclosed
WO-1992013103-A1 INHERITED AND SOMATIC MUTATIONS OF APC GENE IN COLORECTAL CANCER OF HUMANS THE JOHNS HOPKINS UNIVERSITY (US) 1992-08-06 WO disclosed