Carbamic Acid

Carbamic Acid

SCHEMBL9011736

NC(=O)O.c1ccc2c(c1)CCCC2

nearest known ligand 0.65

Full drug profile on Sugi Atlas →

Predicted protein targets (top 20)

geneUniProtsupporting neighboursconfidence
TSHR P16473 2/20 0.65
L3MBTL1 Q9Y468 2/20 0.44
POLB P06746 1/20 0.44
CYP3A4 P08684 1/20 0.44
PARP1 P09874 1/20 0.44
MAPT P10636 1/20 0.44
CYP2C19 P33261 1/20 0.44
RECQL P46063 1/20 0.44
BLM P54132 1/20 0.44
PMP22 Q01453 1/20 0.44
HSD17B10 Q99714 1/20 0.44
TDP1 Q9NUW8 1/20 0.44
SMN1; SMN2 Q16637 2/20 0.44
ALDH1A1 P00352 1/20 0.43
NOTUM Q6P988 1/20 0.43
NPC1 O15118 2/20 0.43
RAB9A P51151 2/20 0.43
MEN1 O00255 1/20 0.43
KMT2A Q03164 1/20 0.43
HDAC9 Q9UKV0 1/20 0.42

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
Carbamic Acid SCHEMBL2175348 0.95 TSHR (0.57) TSHRL3MBTL1POLBCYP3A4PARP1
Bicarbonate SCHEMBL28735118 0.90 TSHR (0.72) TSHRL3MBTL1CYP2C19SMN1; SMN2ALDH1A1
Urea SCHEMBL5312853 0.87 TSHR (0.60) TSHRMAPTCYP2C19SMN1; SMN2ALDH1A1
Oxalic Acid SCHEMBL27358225 0.87 TSHR (0.68) TSHRL3MBTL1POLBSMN1; SMN2ALDH1A1
Benzamide SCHEMBL28706120 0.87 TSHR (0.67) TSHRL3MBTL1POLBCYP3A4PARP1
Hydrogen Peroxide SCHEMBL30110573 0.87 TSHR (0.87) TSHRL3MBTL1MAPTSMN1; SMN2ALDH1A1
Hydrogen Peroxide SCHEMBL298462 0.87 TSHR (0.87) TSHRL3MBTL1MAPTSMN1; SMN2ALDH1A1
SCHEMBL15412375 0.85 TSHR (0.65) TSHRL3MBTL1CYP2C19SMN1; SMN2ALDH1A1
Acetic Acid SCHEMBL3435922 0.85 TSHR (0.65) TSHRSMN1; SMN2ALDH1A1NOTUMNPC1
Benzene SCHEMBL11299980 0.84 TSHR (0.93) TSHRL3MBTL1MAPTHPGDBCL2L1

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 3 patents. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
JP-8245692-A None JP disclosed
JP-H08245692-A TETRAHYDRONAPHTHALENE DERIVATIVE F HOFFMANN LA ROCHE AG 1996-09-24 JP disclosed
US-5529874-A ETHER CARRIER LIQUID AND TONER PARTICLES DISPERSED THEREIN; SUITABLE FOR HIGH SPEED COPYING FUJI XEROX CO., LTD. (JP) 1996-06-25 US disclosed