Predicted protein targets (top 14)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | TP53 | P04637 | 1/20 | 0.52 |
| ▸ | CA2 | P00918 | 2/20 | 0.45 |
| ▸ | GPR84 | Q9NQS5 | 5/20 | 0.43 |
| ▸ | FDPS | P14324 | 4/20 | 0.43 |
| ▸ | FFAR1 | O14842 | 1/20 | 0.43 |
| ▸ | LMNA | P02545 | 1/20 | 0.43 |
| ▸ | DNM1 | Q05193 | 2/20 | 0.42 |
| ▸ | MAPT | P10636 | 1/20 | 0.42 |
| ▸ | LCK | P06239 | 1/20 | 0.42 |
| ▸ | PPARD | Q03181 | 1/20 | 0.42 |
| ▸ | ZDHHC20 | Q5W0Z9 | 1/20 | 0.42 |
| ▸ | ZDHHC2 | Q9UIJ5 | 1/20 | 0.42 |
| ▸ | CA1 | P00915 | 1/20 | 0.41 |
| ▸ | LAP3 | P28838 | 1/20 | 0.41 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL27804635 | 1.00 | TP53 (0.52) | TP53CA2GPR84FDPSFFAR1 | |
| SCHEMBL3189532 | 1.00 | TP53 (0.52) | TP53CA2GPR84FDPSFFAR1 | |
| SCHEMBL11254235 | 1.00 | TP53 (0.52) | TP53CA2GPR84FDPSFFAR1 | |
| SCHEMBL2153897 | 0.98 | TP53 (0.54) | TP53CA2GPR84FDPSFFAR1 | |
| SCHEMBL6128322 | 0.98 | TP53 (0.54) | TP53CA2GPR84FDPSFFAR1 | |
| SCHEMBL7785566 | 0.98 | TP53 (0.54) | TP53CA2GPR84FDPSFFAR1 | |
| SCHEMBL16395754 | 0.98 | TP53 (0.54) | TP53CA2GPR84FDPSFFAR1 | |
| SCHEMBL10695349 | 0.98 | TP53 (0.54) | TP53CA2GPR84FDPSFFAR1 | |
| SCHEMBL6128343 | 0.98 | TP53 (0.54) | TP53CA2GPR84FDPSFFAR1 | |
| SCHEMBL9460109 | 0.98 | TP53 (0.54) | TP53CA2GPR84FDPSFFAR1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-5559098-A | Stable topical formulations with good active ingredient release characteristics, containing at least one lipophilized macrolide antibiotic | ROEHM PHARMA GMBH (DE) | 1996-09-24 | — | — | US | disclosed |
| US-5476843-A | Stable topical formulations with good active ingredient release characteristics, containing at least one lipophilized macrolide antibiotic | ROEHM PHARMA GMBH (DE) | 1995-12-19 | — | — | US | disclosed |