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Sugi Predict / Compounds / SCHEMBL9011895

SCHEMBL9011895

SCHEMBL9011895

COC(=O)c1cccc(CC(=O)Nc2ccc(-c3ccccc3)n(CC(=O)NC(C(C)C)C(O[Si](C)(C)C(C)(C)C)C(F)(F)F)c2=O)c1

nearest known ligand 0.59

Predicted protein targets (top 2)

geneUniProtsupporting neighboursconfidence
▸ ELANE P08246 20/20 0.59
▸ CTRC Q99895 1/20 0.47

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL7284496 0.93 ELANE (0.58) ELANECTRC
SCHEMBL7276466 0.92 ELANE (0.64) ELANECTRC
SCHEMBL7283926 0.89 ELANE (0.62) ELANECTRC
SCHEMBL7284137 0.88 ELANE (0.57) ELANECTRC
SCHEMBL7277022 0.86 ELANE (0.61) ELANECTRC
SCHEMBL7276477 0.85 ELANE (0.60) ELANECTRC
SCHEMBL7276661 0.84 ELANE (0.67) ELANECTRC
SCHEMBL7280555 0.84 ELANE (0.65) ELANECTRC
SCHEMBL7281272 0.84 ELANE (0.58) ELANECTRC
SCHEMBL7301001 0.83 ELANE (0.56) ELANECTRC

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
US-5521179-A Heterocyclic amides ZENECA LIMITED (GB) 1996-05-28 — — US disclosed