Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | HDAC1 | Q13547 | 1/20 | 0.45 |
| ▸ | AR | P10275 | 1/20 | 0.38 |
| ▸ | FDPS | P14324 | 1/20 | 0.38 |
| ▸ | TXN | P10599 | 1/20 | 0.36 |
| ▸ | TXNRD1 | Q16881 | 1/20 | 0.36 |
| ▸ | ADRA2C | P18825 | 2/20 | 0.36 |
| ▸ | ADRA2B | P18089 | 1/20 | 0.36 |
| ▸ | HSD17B10 | Q99714 | 2/20 | 0.36 |
| ▸ | TSHR | P16473 | 1/20 | 0.36 |
| ▸ | CASP1 | P29466 | 1/20 | 0.36 |
| ▸ | TAAR1 | Q96RJ0 | 2/20 | 0.35 |
| ▸ | HTR1A | P08908 | 1/20 | 0.35 |
| ▸ | NPC1 | O15118 | 3/20 | 0.35 |
| ▸ | ALDH1A1 | P00352 | 3/20 | 0.35 |
| ▸ | RAB9A | P51151 | 3/20 | 0.35 |
| ▸ | SMN1; SMN2 | Q16637 | 3/20 | 0.35 |
| ▸ | HPGD | P15428 | 2/20 | 0.35 |
| ▸ | NFKB1 | P19838 | 1/20 | 0.35 |
| ▸ | NFKB2 | Q00653 | 1/20 | 0.35 |
| ▸ | RELA | Q04206 | 1/20 | 0.35 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL9012067 | 0.86 | HDAC1 (0.46) | HDAC1ARFDPSTXNTXNRD1 | |
| SCHEMBL9012538 | 0.85 | HDAC1 (0.42) | HDAC1FDPSTXNTXNRD1ADRA2C | |
| SCHEMBL9365717 | 0.84 | HDAC1 (0.40) | HDAC1TXNTXNRD1HSD17B10TSHR | |
| SCHEMBL9011958 | 0.84 | HDAC1 (0.46) | HDAC1ADRA2CHSD17B10TSHRTAAR1 | |
| SCHEMBL9011970 | 0.83 | HDAC1 (0.41) | HDAC1FDPSADRA2CHSD17B10TSHR | |
| SCHEMBL9362106 | 0.83 | HDAC1 (0.43) | HDAC1FDPSHSD17B10ALDH1A1SMN1; SMN2 | |
| SCHEMBL9012190 | 0.82 | HDAC1 (0.44) | HDAC1FDPSTXNTXNRD1ADRA2C | |
| SCHEMBL9361359 | 0.81 | HDAC1 (0.40) | HDAC1FDPSTXNTXNRD1HSD17B10 | |
| SCHEMBL9361383 | 0.81 | HDAC1 (0.42) | HDAC1HSD17B10ALDH1A1SMN1; SMN2HPGD | |
| SCHEMBL9012305 | 0.81 | HDAC1 (0.40) | HDAC1FDPSTXNTXNRD1HSD17B10 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 3 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-5523317-A | ADMINISTERING IMIDAZOLE DERIVATIVE | NIPPON CHEMIPHAR CO., LTD. (JP) | 1996-06-04 | — | — | US | disclosed |
| EP-0633026-A1 | Use of imidazole derivative for antihypertensive agent | NIPPON CHEMIPHAR CO., LTD. (JP) | 1995-01-11 | — | — | EP | disclosed |
| EP-0584588-A1 | Anti-ulcer composition containing imidazole derivative | NIPPON CHEMIPHAR CO., LTD. (JP) | 1994-03-02 | — | — | EP | disclosed |