Predicted protein targets (top 6)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | F2 | P00734 | 5/20 | 0.42 |
| ▸ | CMA1 | P23946 | 11/20 | 0.40 |
| ▸ | PRSS1 | P07477 | 3/20 | 0.37 |
| ▸ | XIAP | P98170 | 4/20 | 0.36 |
| ▸ | PRSS2 | P07478 | 1/20 | 0.35 |
| ▸ | PRSS3 | P35030 | 1/20 | 0.35 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL9012408 | 0.89 | F2 (0.42) | F2CMA1PRSS1XIAPPRSS2 | |
| SCHEMBL9011950 | 0.85 | F2 (0.45) | F2CMA1PRSS1XIAPPRSS2 | |
| SCHEMBL9012156 | 0.84 | F2 (0.42) | F2CMA1PRSS1PRSS2PRSS3 | |
| SCHEMBL9012012 | 0.84 | F2 (0.42) | F2CMA1PRSS1XIAPPRSS2 | |
| SCHEMBL9012142 | 0.83 | F2 (0.44) | F2CMA1PRSS1XIAPPRSS2 | |
| SCHEMBL9012149 | 0.83 | F2 (0.44) | F2CMA1PRSS1XIAPPRSS2 | |
| SCHEMBL9012329 | 0.82 | F2 (0.43) | F2CMA1PRSS1XIAPPRSS2 | |
| SCHEMBL9012429 | 0.82 | F2 (0.43) | F2CMA1PRSS1PRSS2PRSS3 | |
| SCHEMBL9012567 | 0.82 | F2 (0.43) | F2CMA1PRSS1XIAPPRSS2 | |
| SCHEMBL9012564 | 0.82 | F2 (0.43) | F2CMA1PRSS1XIAPPRSS2 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-0743320-A2 | Acyl guanidine and amidine prodrugs | BRISTOL-MYERS SQUIBB COMPANY (US) | 1996-11-20 | — | — | EP | claimed |
| EP-0743320-A2 | Acyl guanidine and amidine prodrugs | BRISTOL-MYERS SQUIBB COMPANY (US) | 1996-11-20 | — | — | EP | disclosed |