Predicted protein targets (top 17)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | ACE | P12821 | 6/20 | 0.42 |
| ▸ | ACE2 | Q9BYF1 | 5/20 | 0.42 |
| ▸ | PRCP | P42785 | 1/20 | 0.41 |
| ▸ | F2 | P00734 | 5/20 | 0.39 |
| ▸ | CMA1 | P23946 | 1/20 | 0.36 |
| ▸ | NMUR2 | Q9GZQ4 | 2/20 | 0.34 |
| ▸ | NMUR1 | Q9HB89 | 2/20 | 0.34 |
| ▸ | FKBP1A | P62942 | 1/20 | 0.34 |
| ▸ | BCHE | P06276 | 3/20 | 0.34 |
| ▸ | ACHE | P22303 | 3/20 | 0.34 |
| ▸ | PRSS1 | P07477 | 1/20 | 0.34 |
| ▸ | TMPRSS11D | O60235 | 1/20 | 0.34 |
| ▸ | F10 | P00742 | 1/20 | 0.34 |
| ▸ | CACNA1F | O60840 | 1/20 | 0.34 |
| ▸ | CACNA1D | Q01668 | 1/20 | 0.34 |
| ▸ | CACNA1S | Q13698 | 1/20 | 0.34 |
| ▸ | CACNA1C | Q13936 | 1/20 | 0.34 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL9012313 | 1.00 | ACE (0.42) | ACEACE2PRCPF2CMA1 | |
| SCHEMBL9012200 | 0.98 | ACE (0.42) | ACEACE2PRCPF2CMA1 | |
| SCHEMBL9012210 | 0.98 | ACE (0.42) | ACEACE2PRCPF2CMA1 | |
| SCHEMBL9012094 | 0.94 | ACE (0.46) | ACEACE2PRCPF2CMA1 | |
| SCHEMBL9012364 | 0.94 | ACE (0.46) | ACEACE2PRCPF2CMA1 | |
| SCHEMBL9012616 | 0.93 | ACE (0.42) | ACEACE2PRCPF2CMA1 | |
| SCHEMBL9012317 | 0.93 | ACE (0.42) | ACEACE2PRCPF2CMA1 | |
| SCHEMBL9012303 | 0.93 | ACE (0.42) | ACEACE2PRCPF2CMA1 | |
| SCHEMBL9012610 | 0.93 | ACE (0.42) | ACEACE2PRCPF2CMA1 | |
| SCHEMBL9012029 | 0.93 | ACE (0.43) | ACEACE2PRCPF2CMA1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-0743320-A2 | Acyl guanidine and amidine prodrugs | BRISTOL-MYERS SQUIBB COMPANY (US) | 1996-11-20 | — | — | EP | claimed |
| EP-0743320-A2 | Acyl guanidine and amidine prodrugs | BRISTOL-MYERS SQUIBB COMPANY (US) | 1996-11-20 | — | — | EP | disclosed |