Predicted protein targets (top 4)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | TSHR | P16473 | 2/20 | 0.36 |
| ▸ | TDP1 | Q9NUW8 | 1/20 | 0.33 |
| ▸ | MEN1 | O00255 | 1/20 | 0.30 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.30 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL23200430 | 0.80 | TSHR (0.40) | TSHRTDP1MEN1KMT2A | |
| SCHEMBL9246267 | 0.80 | TSHR (0.35) | TSHRTDP1 | |
| SCHEMBL766965 | 0.80 | TSHR (0.35) | TSHRTDP1 | |
| SCHEMBL15732726 | 0.80 | TSHR (0.34) | TSHRTDP1 | |
| SCHEMBL19559253 | 0.79 | — | — | |
| SCHEMBL4188929 | 0.78 | — | — | |
| SCHEMBL12890924 | 0.78 | — | — | |
| SCHEMBL12890928 | 0.78 | — | — | |
| SCHEMBL16774771 | 0.78 | — | — | |
| SCHEMBL9541746 | 0.78 | — | — |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 3 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-5525506-A | Process for production of avermectins and cultures therefor | PFIZER INC. (US) | 1996-06-11 | — | — | US | disclosed |
| US-5238848-A | Cultures for production of avermectins | PFIZER INC (US) | 1993-08-24 | — | — | US | disclosed |
| US-5077278-A | Parasiticides | PFIZER INC. (US) | 1991-12-31 | — | — | US | disclosed |