Predicted protein targets (top 7)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | F2 | P00734 | 3/20 | 0.43 |
| ▸ | PRSS1 | P07477 | 1/20 | 0.42 |
| ▸ | CMA1 | P23946 | 13/20 | 0.42 |
| ▸ | ACE | P12821 | 1/20 | 0.41 |
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.41 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.39 |
| ▸ | POLB | P06746 | 1/20 | 0.39 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL9012550 | 1.00 | F2 (0.43) | F2PRSS1CMA1ACESMN1; SMN2 | |
| SCHEMBL9012460 | 0.93 | ACE (0.43) | F2PRSS1CMA1ACE | |
| SCHEMBL9012457 | 0.93 | ACE (0.43) | F2PRSS1CMA1ACE | |
| SCHEMBL9012606 | 0.89 | F2 (0.48) | F2PRSS1CMA1ACESMN1; SMN2 | |
| SCHEMBL9012125 | 0.89 | F2 (0.48) | F2PRSS1CMA1ACESMN1; SMN2 | |
| SCHEMBL9012544 | 0.87 | F2 (0.45) | F2PRSS1CMA1ACE | |
| SCHEMBL9012551 | 0.87 | F2 (0.45) | F2PRSS1CMA1ACE | |
| SCHEMBL8818023 | 0.86 | F2 (0.41) | F2PRSS1CMA1ACE | |
| SCHEMBL8818014 | 0.86 | F2 (0.41) | F2PRSS1CMA1ACE | |
| SCHEMBL8820439 | 0.85 | F2 (0.41) | F2PRSS1CMA1ACE |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-0743320-A2 | Acyl guanidine and amidine prodrugs | BRISTOL-MYERS SQUIBB COMPANY (US) | 1996-11-20 | — | — | EP | disclosed |