Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | CHRM2 | P08172 | 3/20 | 0.36 |
| ▸ | HTR1A | P08908 | 2/20 | 0.36 |
| ▸ | ADRA2A | P08913 | 2/20 | 0.36 |
| ▸ | CHRM1 | P11229 | 2/20 | 0.36 |
| ▸ | DRD1 | P21728 | 2/20 | 0.36 |
| ▸ | SLC6A2 | P23975 | 2/20 | 0.36 |
| ▸ | ADRA1A | P35348 | 2/20 | 0.36 |
| ▸ | DRD3 | P35462 | 2/20 | 0.36 |
| ▸ | SLC6A3 | Q01959 | 2/20 | 0.36 |
| ▸ | KCNH2 | Q12809 | 2/20 | 0.36 |
| ▸ | CYP2D6 | P10635 | 1/20 | 0.36 |
| ▸ | OPRM1 | P35372 | 1/20 | 0.36 |
| ▸ | HRH3 | Q9Y5N1 | 1/20 | 0.36 |
| ▸ | MAPK1 | P28482 | 2/20 | 0.36 |
| ▸ | LMNA | P02545 | 3/20 | 0.35 |
| ▸ | TSHR | P16473 | 2/20 | 0.35 |
| ▸ | CHRM4 | P08173 | 2/20 | 0.35 |
| ▸ | CHRM3 | P20309 | 2/20 | 0.35 |
| ▸ | HRH4 | Q9H3N8 | 1/20 | 0.35 |
| ▸ | SMN1; SMN2 | Q16637 | 2/20 | 0.34 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL900627 | 0.92 | CHRM2 (0.38) | CHRM2HTR1AADRA2ACHRM1DRD1 | |
| SCHEMBL900517 | 0.87 | PTPN1 (0.39) | CHRM2HTR1AADRA2ACHRM1DRD1 | |
| SCHEMBL2722470 | 0.85 | BCHE (0.43) | CHRM2HTR1AADRA2ACHRM1DRD1 | |
| SCHEMBL2720563 | 0.85 | CHRM2 (0.40) | CHRM2HTR1AADRA2ACHRM1DRD1 | |
| SCHEMBL2722064 | 0.85 | HRH3 (0.42) | CHRM2HTR1AADRA2ACHRM1DRD1 | |
| SCHEMBL2723191 | 0.84 | DRD3 (0.42) | CHRM2HTR1AADRA2ACHRM1DRD1 | |
| SCHEMBL900461 | 0.84 | DRD3 (0.44) | CHRM2HTR1AADRA2ACHRM1DRD1 | |
| SCHEMBL2720020 | 0.83 | BCHE (0.42) | CHRM2HTR1AADRA2ACHRM1DRD1 | |
| SCHEMBL901049 | 0.83 | AAK1 (0.31) | L3MBTL1 | |
| SCHEMBL2721841 | 0.83 | DRD3 (0.45) | CHRM2HTR1AADRA2ACHRM1DRD1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-2621916-A1 | BENZAZOLE DERIVATIVES AS HISTAMINE H4 RECEPTOR LIGANDS | BIOPROJET (FR) | 2013-08-07 | — | — | EP | disclosed |
| WO-2012041860-A1 | BENZAZOLE DERIVATIVES AS HISTAMINE H4 RECEPTOR LIGANDS | BIOPROJET (FR) | 2012-04-05 | — | — | WO | disclosed |