Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | CYP3A4 | P08684 | 17/20 | 0.60 |
| ▸ | CYP2C9 | P11712 | 11/20 | 0.60 |
| ▸ | CYP2C19 | P33261 | 11/20 | 0.60 |
| ▸ | LMNA | P02545 | 2/20 | 0.60 |
| ▸ | CYP2B6 | P20813 | 1/20 | 0.60 |
| ▸ | CYP3A5 | P20815 | 1/20 | 0.60 |
| ▸ | CYP3A7 | P24462 | 1/20 | 0.60 |
| ▸ | MAPK1 | P28482 | 1/20 | 0.60 |
| ▸ | CYP3A43 | Q9HB55 | 1/20 | 0.60 |
| ▸ | CYP46A1 | Q9Y6A2 | 1/20 | 0.60 |
| ▸ | CYP1A2 | P05177 | 6/20 | 0.59 |
| ▸ | CYP2D6 | P10635 | 6/20 | 0.59 |
| ▸ | KCNH2 | Q12809 | 3/20 | 0.56 |
| ▸ | HSP90AA1 | P07900 | 1/20 | 0.55 |
| ▸ | CYP19A1 | P11511 | 1/20 | 0.55 |
| ▸ | CYP11B1 | P15538 | 1/20 | 0.55 |
| ▸ | CYP11B2 | P19099 | 1/20 | 0.55 |
| ▸ | ADRA1A | P35348 | 1/20 | 0.55 |
| ▸ | CYP51A1 | Q16850 | 1/20 | 0.55 |
| ▸ | ABCG2 | Q9UNQ0 | 1/20 | 0.48 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL9013755 | 1.00 | CYP3A4 (0.60) | CYP3A4CYP2C9CYP2C19LMNACYP2B6 | |
| SCHEMBL9266528 | 0.86 | CYP3A4 (0.62) | CYP3A4CYP2C9CYP2C19LMNACYP2B6 | |
| Genaconazole SCHEMBL8937940 | 0.86 | CYP3A4 (0.67) | CYP3A4CYP2C9CYP2C19LMNACYP2B6 | |
| Genaconazole SCHEMBL9774648 | 0.86 | CYP3A4 (0.67) | CYP3A4CYP2C9CYP2C19LMNACYP2B6 | |
| Genaconazole SCHEMBL8937907 | 0.86 | CYP3A4 (0.67) | CYP3A4CYP2C9CYP2C19LMNACYP2B6 | |
| Genaconazole SCHEMBL1455652 | 0.86 | CYP3A4 (0.67) | CYP3A4CYP2C9CYP2C19LMNACYP2B6 | |
| Genaconazole SCHEMBL30011920 | 0.86 | CYP3A4 (0.67) | CYP3A4CYP2C9CYP2C19LMNACYP2B6 | |
| SCHEMBL9012973 | 0.85 | CYP3A4 (0.61) | CYP3A4CYP2C9CYP2C19LMNACYP2B6 | |
| SCHEMBL9119825 | 0.85 | CYP3A4 (0.66) | CYP3A4CYP2C9CYP2C19LMNACYP2B6 | |
| SCHEMBL9013065 | 0.85 | CYP3A4 (0.60) | CYP3A4CYP2C9CYP2C19LMNACYP2B6 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 5 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-5393769-A | Thio-, sulfinyl- or sulfonyl-substituted | SANKYO COMPANY, LIMITED (JP) | 1995-02-28 | — | — | US | claimed |
| EP-0473387-A2 | Anti-fungal triazole derivatives, their preparation and uses | Sankyo Company Limited (JP) | 1992-03-04 | — | — | EP | claimed |
| US-5489606-A | FUNGICIDES, HUMAN, VETERNARY MEDICINE | SANKYO COMPANY, LIMITED (JP) | 1996-02-06 | — | — | US | disclosed |
| US-5393769-A | Thio-, sulfinyl- or sulfonyl-substituted | SANKYO COMPANY, LIMITED (JP) | 1995-02-28 | — | — | US | disclosed |
| EP-0473387-A2 | Anti-fungal triazole derivatives, their preparation and uses | Sankyo Company Limited (JP) | 1992-03-04 | — | — | EP | disclosed |