SCHEMBL9013520

SCHEMBL9013520

CCCCCC1(CCCCC2CCC(c3ccc(C(N)=O)cc3)CC2)CCCCC1

nearest known ligand 0.70

Predicted protein targets (top 20)

geneUniProtsupporting neighboursconfidence
CYP2C9 P11712 1/20 0.62
ALDH1A1 P00352 1/20 0.48
LMNA P02545 1/20 0.48
MAPT P10636 1/20 0.48
MEN1 O00255 3/20 0.46
KMT2A Q03164 3/20 0.46
MAPK1 P28482 2/20 0.46
DGAT1 O75907 4/20 0.36
SOAT1 P35610 1/20 0.36
OPRM1 P35372 1/20 0.36
OPRD1 P41143 1/20 0.36
SPHK1 Q9NYA1 2/20 0.36
GPR119 Q8TDV5 1/20 0.36
PARP15 Q460N3 2/20 0.35
PARP10 Q53GL7 2/20 0.35
PARP2 Q9UGN5 1/20 0.34
S1PR1 P21453 1/20 0.34
SGPL1 O95470 1/20 0.34
APAF1 O14727 1/20 0.34
RGS12 O14924 1/20 0.34

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL9013292 0.89 CYP2C9 (0.47) CYP2C9ALDH1A1LMNAMAPTMEN1
SCHEMBL11340158 0.87 CYP2C9 (0.81) CYP2C9ALDH1A1LMNAMAPTMEN1
SCHEMBL11340160 0.87 CYP2C9 (0.81) CYP2C9ALDH1A1LMNAMAPTMEN1
SCHEMBL10832483 0.86 CYP2C9 (0.79) CYP2C9ALDH1A1LMNAMAPTMEN1
SCHEMBL10832486 0.86 CYP2C9 (0.79) CYP2C9ALDH1A1LMNAMAPTMEN1
SCHEMBL10832489 0.86 CYP2C9 (0.79) CYP2C9ALDH1A1LMNAMAPTMEN1
SCHEMBL22258797 0.86 CYP2C9 (0.79) CYP2C9ALDH1A1LMNAMAPTMEN1
SCHEMBL9013289 0.84 CYP2C9 (0.42) CYP2C9ALDH1A1LMNAMAPTMEN1
SCHEMBL11524858 0.84 CYP2C9 (0.75) CYP2C9ALDH1A1LMNAMAPTMEN1
SCHEMBL9973108 0.84 CYP2C9 (0.75) CYP2C9ALDH1A1LMNAMAPTMEN1

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 3 patents. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
EP-0568040-B1 Cyclohexane derivative and liquid crystal composition containing the same CHISSO CORP (JP) 1996-12-04 EP disclosed
US-5468421-A Cyclohexane derivative and liquid crystal composition containing the same CHISSO CORPORATION (JP) 1995-11-21 US disclosed
EP-0568040-A1 Cyclohexane derivative and liquid crystal composition containing the same CHISSO CORPORATION (JP) 1993-11-03 EP disclosed