Predicted protein targets (top 15)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | ALDH1A1 | P00352 | 4/20 | 0.48 |
| ▸ | KDM4E | B2RXH2 | 3/20 | 0.48 |
| ▸ | ELANE | P08246 | 4/20 | 0.46 |
| ▸ | TSPO | P30536 | 1/20 | 0.45 |
| ▸ | RAB9A | P51151 | 1/20 | 0.44 |
| ▸ | TDP1 | Q9NUW8 | 1/20 | 0.43 |
| ▸ | F2 | P00734 | 1/20 | 0.43 |
| ▸ | PLAU | P00749 | 1/20 | 0.43 |
| ▸ | TSHR | P16473 | 1/20 | 0.43 |
| ▸ | POLB | P06746 | 1/20 | 0.43 |
| ▸ | MAPT | P10636 | 1/20 | 0.43 |
| ▸ | CREBBP | Q92793 | 1/20 | 0.43 |
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.43 |
| ▸ | LMNA | P02545 | 1/20 | 0.43 |
| ▸ | GLA | P06280 | 1/20 | 0.42 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL4636351 | 0.82 | KDM4E (0.51) | ALDH1A1KDM4ERAB9ATSHRMAPT | |
| SCHEMBL12479910 | 0.80 | KDM4E (0.37) | ALDH1A1KDM4EELANETSPORAB9A | |
| SCHEMBL9678983 | 0.80 | POLB (0.47) | ALDH1A1KDM4EELANEF2PLAU | |
| SCHEMBL28208567 | 0.79 | POLB (0.46) | ALDH1A1KDM4EELANETSPORAB9A | |
| SCHEMBL28546173 | 0.77 | POLB (0.44) | ALDH1A1KDM4EELANETSPOF2 | |
| SCHEMBL29469528 | 0.77 | NTRK1 (0.58) | ALDH1A1KDM4EELANETSPORAB9A | |
| SCHEMBL1002968 | 0.77 | NTRK1 (0.58) | ALDH1A1KDM4EELANETSPORAB9A | |
| SCHEMBL1906715 | 0.76 | POLB (0.55) | ALDH1A1KDM4ETSPOPOLBMAPT | |
| SCHEMBL11215785 | 0.76 | FNTA (0.51) | ALDH1A1KDM4ETSPORAB9ATDP1 | |
| SCHEMBL151122 | 0.72 | KDM4E (0.71) | ALDH1A1KDM4ETSPORAB9ATDP1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-0635490-B1 | Process for the preparation of N-ethylcarbazole | HOECHST AG (DE) | 1996-12-11 | — | — | EP | disclosed |
| EP-0635490-A1 | Process for the preparation of N-ethylcarbazole | HOECHST AKTIENGESELLSCHAFT (DE) | 1995-01-25 | — | — | EP | disclosed |