Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | CCR1 | P32246 | 4/20 | 0.38 |
| ▸ | CCR5 | P51681 | 4/20 | 0.38 |
| ▸ | CCR8 | P51685 | 4/20 | 0.38 |
| ▸ | PIK3CD | O00329 | 1/20 | 0.37 |
| ▸ | LMNA | P02545 | 6/20 | 0.34 |
| ▸ | MEN1 | O00255 | 5/20 | 0.34 |
| ▸ | KMT2A | Q03164 | 5/20 | 0.34 |
| ▸ | POLB | P06746 | 1/20 | 0.34 |
| ▸ | KDM4E | B2RXH2 | 5/20 | 0.33 |
| ▸ | TP53 | P04637 | 4/20 | 0.33 |
| ▸ | HSP90AA1 | P07900 | 4/20 | 0.33 |
| ▸ | MAPT | P10636 | 3/20 | 0.33 |
| ▸ | HTT | P42858 | 3/20 | 0.33 |
| ▸ | SMN1; SMN2 | Q16637 | 3/20 | 0.33 |
| ▸ | TDP1 | Q9NUW8 | 3/20 | 0.33 |
| ▸ | ALOX12 | P18054 | 2/20 | 0.33 |
| ▸ | ALDH1A1 | P00352 | 2/20 | 0.33 |
| ▸ | ALOX15 | P16050 | 2/20 | 0.33 |
| ▸ | SLC6A2 | P23975 | 2/20 | 0.33 |
| ▸ | USP2 | O75604 | 2/20 | 0.33 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL9014297 | 1.00 | CCR1 (0.38) | CCR1CCR5CCR8PIK3CDLMNA | |
| SCHEMBL1073354 | 0.83 | CCR1 (0.50) | CCR1CCR5CCR8LMNAMEN1 | |
| Hydrochloric Acid SCHEMBL11825124 | 0.81 | CCR1 (0.48) | CCR1CCR5CCR8LMNAMEN1 | |
| SCHEMBL1071219 | 0.81 | CCR1 (0.48) | CCR1CCR5CCR8LMNAMEN1 | |
| SCHEMBL9131899 | 0.79 | CCR1 (0.46) | CCR1CCR5CCR8LMNAMEN1 | |
| SCHEMBL9014390 | 0.78 | CCR1 (0.65) | CCR1CCR5CCR8LMNAMEN1 | |
| SCHEMBL9014369 | 0.78 | CCR1 (0.65) | CCR1CCR5CCR8LMNAMEN1 | |
| Dipyridyl SCHEMBL27618154 | 0.77 | KDM4E (0.54) | CCR1CCR5CCR8LMNAMEN1 | |
| SCHEMBL13328096 | 0.72 | CCR1 (0.75) | CCR1CCR5CCR8LMNAMEN1 | |
| SCHEMBL1645534 | 0.69 | KDM4E (0.61) | CCR1CCR5CCR8LMNAPOLB |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-0526603-B1 | Use of Mono, Bis or Tris (2,2'-substituted Bipyridine) complexes of a transition metal as mediators for current sensors | ASULAB SA (CH) | 1996-12-04 | — | — | EP | claimed |
| US-5393903-A | Mediator composition for coating an electrode of an amperometric sensor; for glucose testing in biological fluids | ASULAB S.A. (CH) | 1995-02-28 | — | — | US | claimed |