Predicted protein targets (top 17)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | PTGIR | P43119 | 5/20 | 0.56 |
| ▸ | PTGDR | Q13258 | 1/20 | 0.56 |
| ▸ | TBXAS1 | P24557 | 3/20 | 0.46 |
| ▸ | MRGPRX4 | Q96LA9 | 1/20 | 0.40 |
| ▸ | HTT | P42858 | 1/20 | 0.38 |
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.38 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.36 |
| ▸ | PDCD1 | Q15116 | 1/20 | 0.36 |
| ▸ | CD274 | Q9NZQ7 | 1/20 | 0.36 |
| ▸ | NAPRT | Q6XQN6 | 1/20 | 0.35 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.35 |
| ▸ | BRD4 | O60885 | 1/20 | 0.35 |
| ▸ | NOTUM | Q6P988 | 1/20 | 0.35 |
| ▸ | IDO1 | P14902 | 1/20 | 0.35 |
| ▸ | CMKLR2 | P46091 | 1/20 | 0.35 |
| ▸ | CMKLR1 | Q99788 | 1/20 | 0.35 |
| ▸ | GPR132 | Q9UNW8 | 1/20 | 0.35 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL9014516 | 1.00 | PTGIR (0.56) | PTGIRPTGDRTBXAS1MRGPRX4HTT | |
| SCHEMBL9014196 | 0.95 | PTGIR (0.56) | PTGIRPTGDRTBXAS1MRGPRX4HTT | |
| SCHEMBL9014193 | 0.95 | PTGIR (0.56) | PTGIRPTGDRTBXAS1MRGPRX4HTT | |
| SCHEMBL9014590 | 0.93 | PTGIR (0.68) | PTGIRPTGDRTBXAS1MRGPRX4HTT | |
| SCHEMBL9014597 | 0.93 | PTGIR (0.68) | PTGIRPTGDRTBXAS1MRGPRX4HTT | |
| SCHEMBL9014528 | 0.88 | PTGIR (0.68) | PTGIRPTGDRTBXAS1MRGPRX4HTT | |
| SCHEMBL9014532 | 0.88 | PTGIR (0.68) | PTGIRPTGDRTBXAS1MRGPRX4HTT | |
| SCHEMBL9014484 | 0.86 | PTGIR (0.70) | PTGIRPTGDRTBXAS1KMT2AALDH1A1 | |
| SCHEMBL9014475 | 0.86 | PTGIR (0.70) | PTGIRPTGDRTBXAS1KMT2AALDH1A1 | |
| SCHEMBL9014798 | 0.84 | PTGIR (0.57) | PTGIRPTGDRTBXAS1MRGPRX4 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 3 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-0581187-B1 | Oxime derivatives | ONO PHARMACEUTICAL CO (JP) | 1996-12-04 | — | — | EP | disclosed |
| US-5480998-A | Oxime derivative | ONO PHARMACEUTICAL CO., LTD. (JP) | 1996-01-02 | — | — | US | disclosed |
| EP-0581187-A1 | Oxime derivatives | ONO PHARMACEUTICAL CO., LTD. (JP) | 1994-02-02 | — | — | EP | disclosed |