SCHEMBL9014622

SCHEMBL9014622

O=C(O)COc1cccc2c1CCC(C=CCON=C(Cc1cc[nH]c1)c1ccccc1)C2

nearest known ligand 0.49

Predicted protein targets (top 2)

geneUniProtsupporting neighboursconfidence
PTGIR P43119 19/20 0.49
TBXAS1 P24557 1/20 0.37

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL9014616 1.00 PTGIR (0.49) PTGIRTBXAS1
SCHEMBL9014582 0.85 PTGIR (0.69) PTGIRTBXAS1
SCHEMBL9014586 0.85 PTGIR (0.69) PTGIRTBXAS1
SCHEMBL9014577 0.85 PTGIR (0.49) PTGIRTBXAS1
SCHEMBL9014569 0.85 PTGIR (0.49) PTGIRTBXAS1
SCHEMBL9014574 0.85 PTGIR (0.49) PTGIRTBXAS1
SCHEMBL9014620 0.84 PTGIR (0.49) PTGIRTBXAS1
SCHEMBL9014617 0.84 PTGIR (0.49) PTGIRTBXAS1
SCHEMBL9014244 0.84 PTGIR (0.49) PTGIRTBXAS1
SCHEMBL9014238 0.84 PTGIR (0.49) PTGIRTBXAS1

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
EP-0581187-B1 Oxime derivatives ONO PHARMACEUTICAL CO (JP) 1996-12-04 EP disclosed
EP-0581187-A1 Oxime derivatives ONO PHARMACEUTICAL CO., LTD. (JP) 1994-02-02 EP disclosed