Formamide

Formamide

SCHEMBL9014754

C=CC(O)CCC.NC=O

nearest known ligand 0.35

Full drug profile on Sugi Atlas →

Predicted protein targets (top 20)

geneUniProtsupporting neighboursconfidence
GAPDH P04406 2/20 0.35
TRPA1 O75762 1/20 0.35
DDAH1 O94760 1/20 0.35
MAPT P10636 1/20 0.35
SLC6A3 Q01959 2/20 0.34
TSHR P16473 2/20 0.34
NFKB1 P19838 2/20 0.34
SLC6A2 P23975 1/20 0.34
SLC6A4 P31645 1/20 0.34
BLM P54132 1/20 0.34
MEN1 O00255 1/20 0.34
CYP2D6 P10635 1/20 0.34
CYP2C19 P33261 1/20 0.34
KMT2A Q03164 1/20 0.34
TAS1R3 Q7RTX0 1/20 0.32
TAS1R1 Q7RTX1 1/20 0.32
CHRM1 P11229 1/20 0.31
AKR1A1 P14550 1/20 0.31
CHRM3 P20309 1/20 0.31
HTR2A P28223 1/20 0.31

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL187270 0.88
SCHEMBL7939044 0.88
SCHEMBL6252133 0.88
SCHEMBL10501617 0.74 FFAR4 (0.32) NFKB1FDPS
SCHEMBL17787241 0.73
SCHEMBL10063300 0.73
SCHEMBL187210 0.73
SCHEMBL16845288 0.72
SCHEMBL196889 0.72
SCHEMBL5804837 0.71

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
US-5523495-A REACTING KETONE OR ALDEHYDE WITH A DIHALOPROPENE IN PRESENCE OF ZINC POWDER, WATER AND ACID YIELDS A HALOALLYLCARBINOL WHICH CAN BE DEHALOGENATED WITH A BASE, NONEXPLOSIVE SUMITOMO CHEMICAL COMPANY LIMITED (JP) 1996-06-04 US disclosed