SCHEMBL9015138

SCHEMBL9015138

C[C@]12CC[C@H]3[C@@H](CCC4=CC(=O)C=C[C@@]43C)[C@@H]1CC[C@@H]2CC(=O)O

nearest known ligand 0.69

Predicted protein targets (top 5)

geneUniProtsupporting neighboursconfidence
CYP19A1 P11511 13/20 0.69
LMNA P02545 3/20 0.57
MAPT P10636 2/20 0.57
CYP3A4 P08684 1/20 0.57
HSD17B10 Q99714 2/20 0.48

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
Acetone SCHEMBL9504391 0.87 CYP19A1 (0.69) CYP19A1LMNAMAPTCYP3A4
SCHEMBL4199850 0.86 CYP19A1 (0.71) CYP19A1LMNAMAPTCYP3A4
SCHEMBL4199851 0.86 CYP19A1 (0.71) CYP19A1LMNAMAPTCYP3A4
SCHEMBL14027916 0.86 CYP19A1 (0.71) CYP19A1LMNAMAPTCYP3A4
SCHEMBL10882654 0.86 CYP19A1 (0.70) CYP19A1LMNAMAPTCYP3A4
SCHEMBL10895875 0.85 CYP19A1 (0.69) CYP19A1LMNAMAPTCYP3A4
Propionic Acid SCHEMBL29224763 0.84 CYP19A1 (0.85) CYP19A1LMNAMAPTCYP3A4HSD17B10
SCHEMBL29904015 0.84 CYP19A1 (0.71) CYP19A1LMNAMAPTCYP3A4
SCHEMBL3061669 0.83 CYP19A1 (0.47) CYP19A1LMNAMAPTCYP3A4HSD17B10
SCHEMBL2705268 0.83 CYP19A1 (0.73) CYP19A1LMNAMAPTCYP3A4

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
EP-0503388-B1 Pregna-21-oic acid esters TEIKOKU SEIYAKU KK (JP) 1996-12-18 EP disclosed