Predicted protein targets (top 13)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | CYP2C19 | P33261 | 2/20 | 0.61 |
| ▸ | MME | P08473 | 2/20 | 0.33 |
| ▸ | USP2 | O75604 | 1/20 | 0.33 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.33 |
| ▸ | LMNA | P02545 | 1/20 | 0.33 |
| ▸ | CYP1A2 | P05177 | 1/20 | 0.33 |
| ▸ | TSHR | P16473 | 1/20 | 0.33 |
| ▸ | BLM | P54132 | 1/20 | 0.33 |
| ▸ | CACNA2D1 | P54289 | 1/20 | 0.33 |
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.33 |
| ▸ | CYP4F2 | P78329 | 1/20 | 0.32 |
| ▸ | CYP4A11 | Q02928 | 1/20 | 0.32 |
| ▸ | TBXAS1 | P24557 | 2/20 | 0.31 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL9015209 | 0.98 | CYP2C19 (0.65) | CYP2C19MMEUSP2ALDH1A1LMNA | |
| SCHEMBL9015163 | 0.88 | CYP2C19 (0.53) | CYP2C19MMEALDH1A1TSHRCYP4F2 | |
| SCHEMBL9015213 | 0.86 | CYP2C19 (0.57) | CYP2C19MMEUSP2ALDH1A1LMNA | |
| SCHEMBL3707904 | 0.79 | CYP2C19 (0.53) | CYP2C19ALDH1A1LMNACYP1A2SMN1; SMN2 | |
| SCHEMBL4998279 | 0.78 | CYP2C19 (0.47) | CYP2C19MMEALDH1A1CYP4F2CYP4A11 | |
| SCHEMBL3385172 | 0.78 | CYP2C19 (0.95) | CYP2C19MMEUSP2ALDH1A1LMNA | |
| SCHEMBL8902957 | 0.78 | CYP2C19 (0.52) | CYP2C19MMELMNACYP4F2CYP4A11 | |
| SCHEMBL2938022 | 0.78 | CYP2C19 (0.57) | CYP2C19ALDH1A1SMN1; SMN2 | |
| SCHEMBL27258728 | 0.78 | CYP2C19 (0.52) | CYP2C19MME | |
| SCHEMBL27491564 | 0.77 | CYP2C19 (0.55) | CYP2C19MMEUSP2ALDH1A1LMNA |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-5508408-A | LEUKOTRIENE ANTAGONISTS | CIBA-GEIGY CORPORATION (US) | 1996-04-16 | — | — | US | disclosed |