Predicted protein targets (top 4)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | TBXA2R | P21731 | 10/20 | 0.81 |
| ▸ | TBXAS1 | P24557 | 8/20 | 0.53 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.49 |
| ▸ | TSHR | P16473 | 1/20 | 0.47 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL9253596 | 0.90 | TBXA2R (0.67) | TBXA2RTBXAS1ALDH1A1TSHR | |
| SCHEMBL527812 | 0.90 | TBXA2R (1.00) | TBXA2RTBXAS1 | |
| SCHEMBL15052228 | 0.90 | TBXA2R (0.81) | TBXA2RTBXAS1 | |
| SCHEMBL15052324 | 0.87 | TBXA2R (0.77) | TBXA2RTBXAS1 | |
| SCHEMBL9015441 | 0.81 | TBXA2R (0.74) | TBXA2RTBXAS1 | |
| SCHEMBL9257256 | 0.81 | TBXA2R (0.60) | TBXA2RTBXAS1ALDH1A1 | |
| SCHEMBL9248933 | 0.81 | TBXA2R (0.80) | TBXA2RTBXAS1 | |
| SCHEMBL527399 | 0.81 | TBXA2R (0.76) | TBXA2RTBXAS1 | |
| SCHEMBL15078829 | 0.81 | TBXA2R (0.76) | TBXA2RTBXAS1 | |
| SCHEMBL15052559 | 0.81 | TBXA2R (0.62) | TBXA2RTBXAS1ALDH1A1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 3 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-0648741-B1 | 1,2,3,4-Tetrahydronaphthalene, chroman and thiochroman derivatives as antithrombotic agents | ADIR (FR) | 1996-12-18 | — | — | EP | disclosed |
| US-5472979-A | Antithrombotics | ADIR ET COMPAGNIE (FR) | 1995-12-05 | — | — | US | disclosed |
| EP-0648741-A1 | 1,2,3,4-Tetrahydronaphthalene, chroman and thiochroman derivatives as antithrombotic agents | ADIR ET COMPAGNIE (FR) | 1995-04-19 | — | — | EP | disclosed |