SCHEMBL9015690

SCHEMBL9015690

CCCCCCC(Br)[C](Br)Br

nearest known ligand 0.61

Predicted protein targets (top 15)

geneUniProtsupporting neighboursconfidence
LCK P06239 1/20 0.61
PPARD Q03181 1/20 0.61
ZDHHC20 Q5W0Z9 1/20 0.61
ZDHHC2 Q9UIJ5 1/20 0.61
ZDHHC7 Q9NXF8 2/20 0.55
LMNA P02545 1/20 0.46
GPR84 Q9NQS5 3/20 0.41
FDPS P14324 3/20 0.41
SPHK1 Q9NYA1 1/20 0.41
FFAR1 O14842 1/20 0.41
MAPT P10636 1/20 0.40
TSHR P16473 1/20 0.40
THRB P10828 1/20 0.40
DNM1 Q05193 1/20 0.40
FAAH O00519 1/20 0.39

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL960248 0.97 LCK (0.58) LCKPPARDZDHHC20ZDHHC2ZDHHC7
SCHEMBL4303823 0.90
SCHEMBL9548557 0.81 LCK (0.69) LCKPPARDZDHHC20ZDHHC2ZDHHC7
SCHEMBL5974169 0.81 LCK (0.69) LCKPPARDZDHHC20ZDHHC2ZDHHC7
Hydrochloric Acid SCHEMBL27572307 0.79 LCK (0.67) LCKPPARDZDHHC20ZDHHC2ZDHHC7
SCHEMBL16969913 0.79 LCK (0.61) LCKPPARDZDHHC20ZDHHC2ZDHHC7
SCHEMBL962287 0.78
SCHEMBL28246883 0.78 LCK (0.65) LCKPPARDZDHHC20ZDHHC2ZDHHC7
SCHEMBL3548195 0.78 LCK (0.54) LCKPPARDZDHHC20ZDHHC2ZDHHC7
SCHEMBL25477762 0.76 LCK (0.69) LCKPPARDZDHHC20ZDHHC2ZDHHC7

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 4 patents. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
US-5519126-A COMBATTING DISEASES BY BIOCHEMICL INTERVENTION AT THE RNA AND DNA LEVEL UNIVERSITY OF VIRGINIA ALUMNI PATENTS FOUNDATION (US) 1996-05-21 US disclosed
EP-0406309-A4 OLIGONUCLEOTIDE N-ALKYLPHOSPHORAMIDATES 1992-08-19 EP disclosed
EP-0406309-A1 OLIGONUCLEOTIDE N-ALKYLPHOSPHORAMIDATES THE UNIVERSITY OF VIRGINIA ALUMNI PATENTS FOUNDATION (US) 1991-01-09 EP disclosed
WO-1989009221-A1 OLIGONUCLEOTIDE N-ALKYLPHOSPHORAMIDATES UNIVERSITY OF VIRGINIA ALUMNI PATENTS FOUNDATION (US) 1989-10-05 WO disclosed