Predicted protein targets (top 12)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | S1PR2 | O95136 | 5/20 | 0.55 |
| ▸ | S1PR4 | O95977 | 5/20 | 0.55 |
| ▸ | S1PR1 | P21453 | 5/20 | 0.55 |
| ▸ | S1PR3 | Q99500 | 5/20 | 0.55 |
| ▸ | S1PR5 | Q9H228 | 1/20 | 0.55 |
| ▸ | LPAR3 | Q9UBY5 | 6/20 | 0.50 |
| ▸ | LPAR2 | Q9HBW0 | 3/20 | 0.50 |
| ▸ | ANPEP | P15144 | 1/20 | 0.48 |
| ▸ | ERAP2 | Q6P179 | 1/20 | 0.48 |
| ▸ | EPHX1 | P07099 | 5/20 | 0.48 |
| ▸ | FDPS | P14324 | 3/20 | 0.45 |
| ▸ | LPAR1 | Q92633 | 2/20 | 0.45 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL4401995 | 1.00 | S1PR2 (0.55) | S1PR2S1PR4S1PR1S1PR3S1PR5 | |
| SCHEMBL9463216 | 1.00 | S1PR2 (0.55) | S1PR2S1PR4S1PR1S1PR3S1PR5 | |
| SCHEMBL3138275 | 1.00 | S1PR2 (0.55) | S1PR2S1PR4S1PR1S1PR3S1PR5 | |
| SCHEMBL19349752 | 1.00 | S1PR2 (0.55) | S1PR2S1PR4S1PR1S1PR3S1PR5 | |
| SCHEMBL27675016 | 0.98 | S1PR2 (0.53) | S1PR2S1PR4S1PR1S1PR3S1PR5 | |
| SCHEMBL8854391 | 0.98 | S1PR2 (0.52) | S1PR2S1PR4S1PR1S1PR3S1PR5 | |
| SCHEMBL3361662 | 0.90 | — | — | |
| SCHEMBL29895708 | 0.90 | S1PR2 (0.47) | S1PR2S1PR4S1PR1S1PR3S1PR5 | |
| SCHEMBL16774437 | 0.86 | S1PR2 (0.55) | S1PR2S1PR4S1PR1S1PR3S1PR5 | |
| SCHEMBL32665664 | 0.84 | S1PR2 (0.53) | S1PR2S1PR4S1PR1S1PR3S1PR5 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 4 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-5519126-A | COMBATTING DISEASES BY BIOCHEMICL INTERVENTION AT THE RNA AND DNA LEVEL | UNIVERSITY OF VIRGINIA ALUMNI PATENTS FOUNDATION (US) | 1996-05-21 | — | — | US | disclosed |
| EP-0406309-A4 | OLIGONUCLEOTIDE N-ALKYLPHOSPHORAMIDATES | — | 1992-08-19 | — | — | EP | disclosed |
| EP-0406309-A1 | OLIGONUCLEOTIDE N-ALKYLPHOSPHORAMIDATES | THE UNIVERSITY OF VIRGINIA ALUMNI PATENTS FOUNDATION (US) | 1991-01-09 | — | — | EP | disclosed |
| WO-1989009221-A1 | OLIGONUCLEOTIDE N-ALKYLPHOSPHORAMIDATES | UNIVERSITY OF VIRGINIA ALUMNI PATENTS FOUNDATION (US) | 1989-10-05 | — | — | WO | disclosed |