Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | MEN1 | O00255 | 2/20 | 0.46 |
| ▸ | KMT2A | Q03164 | 2/20 | 0.46 |
| ▸ | TDP1 | Q9NUW8 | 1/20 | 0.38 |
| ▸ | TSHR | P16473 | 3/20 | 0.37 |
| ▸ | TP53 | P04637 | 2/20 | 0.37 |
| ▸ | MAPT | P10636 | 2/20 | 0.37 |
| ▸ | HPGD | P15428 | 2/20 | 0.37 |
| ▸ | ALDH1A1 | P00352 | 2/20 | 0.37 |
| ▸ | CYP1A2 | P05177 | 1/20 | 0.37 |
| ▸ | PPARG | P37231 | 1/20 | 0.37 |
| ▸ | HIF1A | Q16665 | 1/20 | 0.37 |
| ▸ | CHRM3 | P20309 | 9/20 | 0.35 |
| ▸ | CHRM2 | P08172 | 8/20 | 0.35 |
| ▸ | CHRM4 | P08173 | 8/20 | 0.35 |
| ▸ | CHRM1 | P11229 | 8/20 | 0.35 |
| ▸ | CHRM5 | P08912 | 7/20 | 0.35 |
| ▸ | GLA | P06280 | 1/20 | 0.35 |
| ▸ | TAAR1 | Q96RJ0 | 1/20 | 0.34 |
| ▸ | DHFR | P00374 | 1/20 | 0.33 |
| ▸ | MAPK1 | P28482 | 1/20 | 0.32 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL30741081 | 0.83 | ESR1 (0.39) | MEN1KMT2ATSHRTP53MAPT | |
| SCHEMBL28897220 | 0.77 | MEN1 (0.39) | MEN1KMT2ATDP1TSHRALDH1A1 | |
| SCHEMBL28798005 | 0.72 | MEN1 (0.35) | MEN1KMT2ATDP1 | |
| SCHEMBL7151905 | 0.69 | MEN1 (0.47) | MEN1KMT2ATDP1TSHRTP53 | |
| SCHEMBL5495958 | 0.69 | TDP1 (0.45) | MEN1KMT2ATDP1TSHRHPGD | |
| SCHEMBL52157 | 0.68 | TAAR1 (0.53) | MEN1KMT2ATDP1MAPTHPGD | |
| SCHEMBL6218838 | 0.68 | MEN1 (0.36) | MEN1KMT2ATDP1TAAR1 | |
| SCHEMBL28456804 | 0.68 | KMT2A (0.43) | MEN1KMT2ATDP1TSHRTP53 | |
| SCHEMBL2466622 | 0.68 | MEN1 (0.36) | MEN1KMT2ATDP1CYP1A2TAAR1 | |
| SCHEMBL28456800 | 0.68 | CHRM2 (0.41) | MEN1KMT2ATDP1ALDH1A1CHRM3 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-5556935-A | POLYURETHANE, POLYCARBODIIMIDE, POLYEPOXIDE | BAYER AKTIENGESELLSCHAFT (DE) | 1996-09-17 | — | — | US | claimed |
| US-5556935-A | POLYURETHANE, POLYCARBODIIMIDE, POLYEPOXIDE | BAYER AKTIENGESELLSCHAFT (DE) | 1996-09-17 | — | — | US | disclosed |