Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | PTPN7 | P35236 | 5/20 | 0.48 |
| ▸ | HMGCR | P04035 | 3/20 | 0.48 |
| ▸ | TSHR | P16473 | 1/20 | 0.47 |
| ▸ | THRB | P10828 | 1/20 | 0.47 |
| ▸ | RAB9A | P51151 | 2/20 | 0.46 |
| ▸ | SMN1; SMN2 | Q16637 | 2/20 | 0.46 |
| ▸ | NPC1 | O15118 | 1/20 | 0.46 |
| ▸ | ATM | Q13315 | 1/20 | 0.46 |
| ▸ | L3MBTL1 | Q9Y468 | 1/20 | 0.46 |
| ▸ | LMNA | P02545 | 1/20 | 0.46 |
| ▸ | HTT | P42858 | 1/20 | 0.46 |
| ▸ | RECQL | P46063 | 2/20 | 0.43 |
| ▸ | TDP1 | Q9NUW8 | 2/20 | 0.43 |
| ▸ | KCNH2 | Q12809 | 1/20 | 0.41 |
| ▸ | KDM4E | B2RXH2 | 1/20 | 0.40 |
| ▸ | MEN1 | O00255 | 1/20 | 0.40 |
| ▸ | USP2 | O75604 | 1/20 | 0.40 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.40 |
| ▸ | POLB | P06746 | 1/20 | 0.40 |
| ▸ | MAPT | P10636 | 1/20 | 0.40 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL1760681 | 1.00 | PTPN7 (0.48) | PTPN7HMGCRTSHRTHRBRAB9A | |
| SCHEMBL5166822 | 1.00 | PTPN7 (0.48) | PTPN7HMGCRTSHRTHRBRAB9A | |
| SCHEMBL514166 | 1.00 | PTPN7 (0.48) | PTPN7HMGCRTSHRTHRBRAB9A | |
| SCHEMBL5167428 | 1.00 | PTPN7 (0.48) | PTPN7HMGCRTSHRTHRBRAB9A | |
| SCHEMBL6561950 | 1.00 | PTPN7 (0.48) | PTPN7HMGCRTSHRTHRBRAB9A | |
| SCHEMBL9755595 | 1.00 | PTPN7 (0.48) | PTPN7HMGCRTSHRTHRBRAB9A | |
| SCHEMBL1602080 | 1.00 | PTPN7 (0.48) | PTPN7HMGCRTSHRTHRBRAB9A | |
| SCHEMBL9015862 | 1.00 | PTPN7 (0.48) | PTPN7HMGCRTSHRTHRBRAB9A | |
| SCHEMBL9015927 | 1.00 | PTPN7 (0.48) | PTPN7HMGCRTSHRTHRBRAB9A | |
| SCHEMBL54883 | 1.00 | — | — |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 4 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-2142164-B1 | COSMETIC COMPOSITIONS COMPRISING ESTERS BASED ON 2-PROPYLHEPTANOIC ACID | COGNIS IP MAN GMBH (DE) | 2012-07-04 | — | — | EP | claimed |
| EP-0748823-A1 | Catalyst composition and process for the production of olefinic polymers | NIPPON OIL CO. LTD. (JP) | 1996-12-18 | — | — | EP | disclosed |
| US-4988716-A | Inhibitors of slow reacting substance of anaphylaxis | SCHERING CORPORATION (US) | 1991-01-29 | — | — | US | disclosed |
| US-4798842-A | Inhibitors of slow reacting substance of anaphylaxis | SCHERING CORPORATION (US) | 1989-01-17 | — | — | US | disclosed |