Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | NOTUM | Q6P988 | 1/20 | 0.50 |
| ▸ | TRPV1 | Q8NER1 | 1/20 | 0.49 |
| ▸ | POLQ | O75417 | 1/20 | 0.45 |
| ▸ | HTT | P42858 | 1/20 | 0.43 |
| ▸ | GAA | P10253 | 3/20 | 0.42 |
| ▸ | HPGD | P15428 | 1/20 | 0.42 |
| ▸ | KMT2A | Q03164 | 2/20 | 0.42 |
| ▸ | KDM4E | B2RXH2 | 1/20 | 0.42 |
| ▸ | ALDH1A1 | P00352 | 2/20 | 0.41 |
| ▸ | APP | P05067 | 1/20 | 0.41 |
| ▸ | HCAR3 | P49019 | 1/20 | 0.41 |
| ▸ | HCAR2 | Q8TDS4 | 1/20 | 0.41 |
| ▸ | KCNA5 | P22460 | 1/20 | 0.41 |
| ▸ | MLYCD | O95822 | 1/20 | 0.40 |
| ▸ | MEN1 | O00255 | 1/20 | 0.40 |
| ▸ | MAPT | P10636 | 1/20 | 0.40 |
| ▸ | F7 | P08709 | 1/20 | 0.40 |
| ▸ | F3 | P13726 | 1/20 | 0.40 |
| ▸ | SARM1 | Q6SZW1 | 1/20 | 0.40 |
| ▸ | SIRT2 | Q8IXJ6 | 1/20 | 0.40 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL965251 | 0.83 | NOTUM (0.51) | NOTUMTRPV1POLQHTTGAA | |
| SCHEMBL3576501 | 0.83 | NOTUM (0.51) | NOTUMTRPV1POLQHTTGAA | |
| SCHEMBL3159549 | 0.82 | NOTUM (0.48) | NOTUMTRPV1POLQHTTGAA | |
| SCHEMBL16295458 | 0.81 | NOTUM (0.50) | NOTUMTRPV1POLQHTTGAA | |
| Hydrochloric Acid SCHEMBL5349528 | 0.81 | NOTUM (0.50) | NOTUMTRPV1POLQHTTGAA | |
| SCHEMBL427122 | 0.81 | NOTUM (0.50) | NOTUMTRPV1POLQHTTGAA | |
| SCHEMBL1577273 | 0.81 | NOTUM (0.50) | NOTUMTRPV1POLQHTTGAA | |
| SCHEMBL11836720 | 0.81 | KDM4E (0.44) | NOTUMTRPV1POLQHTTGAA | |
| Hydrochloric Acid SCHEMBL17785084 | 0.80 | NOTUM (0.49) | NOTUMTRPV1POLQHTTGAA | |
| SCHEMBL25417551 | 0.80 | NOTUM (0.46) | NOTUMTRPV1POLQHTTGAA |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-0749425-A1 | NEW PIPERAZINE DERIVATIVES AND METHODS FOR THE PREPARATION THEREOF AND COMPOSITIONS CONTAINING THE SAME | SAMJIN PHARM. CO., LTD. (KR) | 1996-12-27 | — | — | EP | disclosed |