SCHEMBL901661

SCHEMBL901661

Oc1cc(Cl)cc(Sc2cccc(Cl)c2)c1O

nearest known ligand 0.45

Predicted protein targets (top 20)

geneUniProtsupporting neighboursconfidence
RHEB Q15382 3/20 0.45
SLC6A2 P23975 2/20 0.44
SLC6A3 Q01959 2/20 0.44
SLC6A4 P31645 1/20 0.44
MEN1 O00255 3/20 0.44
ALDH1A1 P00352 3/20 0.44
HPGD P15428 3/20 0.44
KMT2A Q03164 3/20 0.44
CYP3A4 P08684 2/20 0.44
ALOX15 P16050 2/20 0.44
HTT P42858 2/20 0.44
HIF1A Q16665 2/20 0.44
HSD17B10 Q99714 2/20 0.44
KDM4E B2RXH2 2/20 0.44
TSHR P16473 2/20 0.44
POLB P06746 2/20 0.44
PLA2G1B P04054 1/20 0.44
HSP90AA1 P07900 1/20 0.44
CYP2D6 P10635 1/20 0.44
CYP2C9 P11712 1/20 0.44

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL28016296 0.79 SLC6A2 (0.54) RHEBSLC6A2SLC6A3SLC6A4MEN1
SCHEMBL30688805 0.74 POLB (0.56) RHEBSLC6A2SLC6A3SLC6A4MEN1
SCHEMBL2282611 0.74 POLB (0.56) RHEBSLC6A2SLC6A3SLC6A4MEN1
SCHEMBL29543630 0.74 POLB (0.56) RHEBSLC6A2SLC6A3SLC6A4MEN1
SCHEMBL10596007 0.72 POLB (0.55) RHEBSLC6A2SLC6A3SLC6A4MEN1
SCHEMBL27777645 0.72 SLC6A2 (0.44) RHEBSLC6A2SLC6A3SLC6A4MEN1
SCHEMBL10708413 0.71 POLB (0.62) RHEBSLC6A2SLC6A3SLC6A4MEN1
SCHEMBL11817929 0.71 SLC6A2 (0.57) RHEBSLC6A2SLC6A3SLC6A4MEN1
SCHEMBL28016292 0.71 NR1H2 (0.56) RHEBSLC6A2SLC6A3SLC6A4MEN1
SCHEMBL4337764 0.70 HSD17B10 (0.59) RHEBSLC6A2SLC6A3SLC6A4MEN1

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 138 patents — showing the first 20. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
EP-2943559-B1 ANTIMICROBIAL ABRASIVE CREAM TYPE CLEANING COMPOSITIONS FOR INANIMATE HARD SURFACES RECKITT BENCKISER BRANDS LTD (GB) 2023-04-26 EP disclosed
EP-2872185-B1 LAVATORY TREATMENT DEVICE RECKITT BENCKISER LLC (US) 2020-08-19 EP disclosed
US-20200253201-A1 Sprayable, Aqueous Alcoholic Microbicidal Compositions Comprising Zinc Ions RECKITT BENCKISER LLC (US) 2020-08-13 US disclosed
US-10660331-B2 Sprayable, aqueous alcoholic microbicidal compositions comprising zinc ions RECKITT BENCKISER LLC (US) 2020-05-26 US disclosed
EP-2866559-B1 AQUEOUS ALCOHOLIC MICROBICIDAL COMPOSITIONS COMPRISING ZINC IONS RECKITT BENCKISER LLC (US) 2019-12-25 EP disclosed
US-10238105-B2 Sprayable, aqueous alcoholic microbicidal compositions comprising zinc ions RECKITT BENCKISER LLC (US) 2019-03-26 US disclosed
EP-3104835-B1 PULVURENT EFFERVESCENT TOPICAL TREATMENT COMPOSITION RECKITT BENCKISER LLC (US) 2019-02-13 EP disclosed
US-20180295837-A1 Sprayable, Aqueous Alcoholic Microbicidal Compositions Comprising Zinc Ions RECKITT BENCKISER LLC (US) 2018-10-18 US disclosed
US-9877484-B2 Pulvurent effervescent topical treatment composition RECKITT BENCKISER LLC (US) 2018-01-30 US disclosed
US-9839220-B2 Antimicrobial abrasive cream type cleaning compositions for inanimate hard surfaces RECKITT BENCKISER (BRANDS) LIMITED (GB) 2017-12-12 US disclosed
EP-1201229-A1 Concentrated liquid formulations comprising a microbicidally active ingredient Ciba SC Holding AG (CH) 2002-05-02 EP disclosed
WO-2002026268-A2 HARD SURFACE CLEANING AND DISINFECTING COMPOSITIONS RECKITT BENCKISER INC. (US) 2002-04-04 WO disclosed
US-6358906-B1 CHLORINATED AND/OR BROMINATED 2-HYDROXYDIPHENYL ETHER DERIVATIVE; ALCOHOL, SULFONATE, CARBOXYLIC ACID AND WATER; HAND SOAP CIBA SPECIALTY CHEMICALS CORPORATION 2002-03-19 US disclosed
US-6204230-B1 IN ANTIBACTERIAL CLEANSING COMPOSITIONS USED TO CLEANSE SKIN AND TO DESTROY BACTERIA AND OTHER MICROORGANISMS PRESENT ON THE SKIN, ESPECIALLY THE HANDS, ARMS, AND FACE OF THE USER OR FOR CLEAING HARD SURFACES THE DIAL CORPORATION 2001-03-20 US disclosed
US-6136771-A COMPRISING PHENOLIC ANTIBACTERIAL AGENT, DISINFECTING ALCOHOL, GELLING AGENT, WATER THE DIAL CORPORATION (US) 2000-10-24 US disclosed
US-6107261-A PHENOLIC ANTIBACTERIAL AGENT, A SURFACTANT, HYDROTROPE, WATER SOLUBLE HYDRIC SOLVENT, AND WATER, WHEREIN A PERCENT SATURATION OF THE ANTIBACTERIAL AGENT IN A CONTINUOUS AQUEOUS PHASE OF THE COMPOSITION IS AT LEAST 50% THE DIAL CORPORATION (US) 2000-08-22 US disclosed
EP-0914085-A2 CONCENTRATED LIQUID ACCUMULATIONS COMPRISING A MICROBICIDALLY ACTIVE INGREDIENT Ciba SC Holding AG (CH) 1999-05-12 EP disclosed
WO-1997046218-A2 CONCENTRATED LIQUID FORMULATIONS COMPRISING A MICROBICIDALLY ACTIVE INGREDIENT CIBA SPECIALTY CHEMICALS HOLDING INC. (CH) 1997-12-11 WO disclosed
EP-0777717-A2 SURFACE-ACTIVE FORMULATIONS Ciba SC Holding AG (CH) 1997-06-11 EP disclosed
WO-1996006153-A2 SURFACE-ACTIVE FORMULATIONS CIBA SPECIALTY CHEMICALS HOLDING INC. (CH) 1996-02-29 WO disclosed

Patent text — is the patent's own abstract consistent with the prediction?

For each of this compound's patents that has machine-readable text (4 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.

PatentTitleText reads most aboutPredicted target · text-rank
US-10660331-B2 Sprayable, aqueous alcoholic microbicidal compositions comprising zinc ions AP3M1, AP1M1, AP2M1 RHEB 4396/4885SLC6A2 3487/4885SLC6A3 2448/4885
US-10238105-B2 Sprayable, aqueous alcoholic microbicidal compositions comprising zinc ions AP3M1, AP1M1, AP2M1 RHEB 4396/4885SLC6A2 3487/4885SLC6A3 2448/4885
US-20180295837-A1 Sprayable, Aqueous Alcoholic Microbicidal Compositions Comprising Zinc Ions AP3M1, AP1M1, AP2M1 RHEB 4396/4885SLC6A2 3487/4885SLC6A3 2448/4885
US-20200253201-A1 Sprayable, Aqueous Alcoholic Microbicidal Compositions Comprising Zinc Ions AP3M1, AP1M1, AP2M1 RHEB 4396/4885SLC6A2 3487/4885SLC6A3 2448/4885

“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.