Predicted protein targets (top 18)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.55 |
| ▸ | HPGD | P15428 | 1/20 | 0.55 |
| ▸ | PPARG | P37231 | 3/20 | 0.50 |
| ▸ | PPARA | Q07869 | 3/20 | 0.50 |
| ▸ | LPL | P06858 | 2/20 | 0.50 |
| ▸ | LIPG | Q9Y5X9 | 2/20 | 0.50 |
| ▸ | SPHK2 | Q9NRA0 | 1/20 | 0.50 |
| ▸ | SPHK1 | Q9NYA1 | 1/20 | 0.50 |
| ▸ | KCNH2 | Q12809 | 1/20 | 0.48 |
| ▸ | DRD2 | P14416 | 1/20 | 0.47 |
| ▸ | OPRM1 | P35372 | 1/20 | 0.47 |
| ▸ | DRD3 | P35462 | 1/20 | 0.47 |
| ▸ | OPRD1 | P41143 | 1/20 | 0.47 |
| ▸ | OPRK1 | P41145 | 1/20 | 0.47 |
| ▸ | CYP4F2 | P78329 | 1/20 | 0.47 |
| ▸ | CYP4A11 | Q02928 | 1/20 | 0.47 |
| ▸ | THRA | P10827 | 1/20 | 0.46 |
| ▸ | THRB | P10828 | 1/20 | 0.46 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL10724585 | 0.89 | HPGD (0.61) | ALDH1A1HPGD | |
| SCHEMBL5254287 | 0.87 | HPGD (0.57) | ALDH1A1HPGDPPARGCYP4F2CYP4A11 | |
| SCHEMBL5254289 | 0.87 | HPGD (0.57) | ALDH1A1HPGDPPARGCYP4F2CYP4A11 | |
| SCHEMBL27671417 | 0.85 | PPARG (0.50) | PPARGPPARALPLLIPGSPHK2 | |
| SCHEMBL9506855 | 0.85 | PPARG (0.50) | PPARGPPARALPLLIPGSPHK2 | |
| SCHEMBL9508836 | 0.85 | PPARG (0.50) | PPARGPPARALPLLIPGSPHK2 | |
| SCHEMBL9508797 | 0.85 | PPARG (0.50) | PPARGPPARALPLLIPGSPHK2 | |
| SCHEMBL9504753 | 0.85 | PPARG (0.50) | PPARGPPARALPLLIPGSPHK2 | |
| SCHEMBL9507514 | 0.85 | PPARG (0.50) | PPARGPPARALPLLIPGSPHK2 | |
| SCHEMBL9507490 | 0.85 | PPARG (0.50) | PPARGPPARALPLLIPGSPHK2 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-0453010-B1 | Copolymer compositions comprising a copolymer and one or more lubricating additives | SHELL INT RESEARCH (NL) | 1996-06-05 | — | — | EP | disclosed |
| EP-0453010-A1 | Copolymer compositions comprising a copolymer and one or more lubricating additives | SHELL INTERNATIONALE RESEARCHMAATSCHAPPIJ B.V. (NL) | 1991-10-23 | — | — | EP | disclosed |