SCHEMBL9017415

SCHEMBL9017415

O=C(O)c1cc2ccccc2cc1O.[KH].[KH]

nearest known ligand 0.68

Predicted protein targets (top 20)

geneUniProtsupporting neighboursconfidence
GRIN2D O15399 1/20 0.63
GRIN2A Q12879 1/20 0.63
GRIN2B Q13224 1/20 0.63
GRIN2C Q14957 1/20 0.63
ACMSD Q8TDX5 4/20 0.59
IDO1 P14902 1/20 0.59
MAPT P10636 3/20 0.58
MEN1 O00255 2/20 0.58
KMT2A Q03164 2/20 0.58
MITF O75030 1/20 0.58
GAA P10253 1/20 0.58
NCOA1 Q15788 1/20 0.58
TDP1 Q9NUW8 1/20 0.58
NCOA3 Q9Y6Q9 1/20 0.58
KDM4E B2RXH2 3/20 0.53
ALDH1A1 P00352 3/20 0.53
HPGD P15428 2/20 0.53
CA12 O43570 1/20 0.52
CA1 P00915 1/20 0.52
CA2 P00918 1/20 0.52

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL7181714 1.00 GRIN2D (0.63) GRIN2DGRIN2AGRIN2BGRIN2CACMSD
SCHEMBL29358330 0.98 GRIN2D (0.66) GRIN2DGRIN2AGRIN2BGRIN2CACMSD
SCHEMBL6460 0.98 GRIN2D (0.66) GRIN2DGRIN2AGRIN2BGRIN2CACMSD
SCHEMBL8411324 0.96 GRIN2D (0.63) GRIN2DGRIN2AGRIN2BGRIN2CACMSD
SCHEMBL6697931 0.96 GRIN2D (0.63) GRIN2DGRIN2AGRIN2BGRIN2CACMSD
SCHEMBL4956923 0.96 GRIN2D (0.63) GRIN2DGRIN2AGRIN2BGRIN2CACMSD
Potassium SCHEMBL7181725 0.96 GRIN2D (0.63) GRIN2DGRIN2AGRIN2BGRIN2CACMSD
SCHEMBL10647693 0.96 GRIN2D (0.63) GRIN2DGRIN2AGRIN2BGRIN2CACMSD
Water SCHEMBL8972153 0.96 GRIN2D (0.63) GRIN2DGRIN2AGRIN2BGRIN2CACMSD
SCHEMBL6697937 0.96 GRIN2D (0.63) GRIN2DGRIN2AGRIN2BGRIN2CACMSD

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 3 patents. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
US-5543564-A Process for releasing acidic organic compounds from salts thereof by carbon dioxide HOECHST AKTIENGESELLSCHAFT (DE) 1996-08-06 US disclosed
EP-0066205-B1 PROCESS FOR PREPARATION OF 2-HYDROXYNAPHTHALENE-3-CARBOXYLIC ACID Kabushiki Kaisha Ueno Seiyaku Oyo Kenkyujo (JP) 1985-09-04 EP disclosed
EP-0066205-A1 Process for preparation of 2-hydroxynaphthalene-3-carboxylic acid Kabushiki Kaisha Ueno Seiyaku Oyo Kenkyujo (JP) 1982-12-08 EP disclosed