Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | HPGD | P15428 | 9/20 | 0.54 |
| ▸ | ALDH1A1 | P00352 | 7/20 | 0.54 |
| ▸ | KDM4E | B2RXH2 | 6/20 | 0.54 |
| ▸ | SMN1; SMN2 | Q16637 | 4/20 | 0.54 |
| ▸ | CA1 | P00915 | 3/20 | 0.54 |
| ▸ | CA9 | Q16790 | 3/20 | 0.54 |
| ▸ | CA12 | O43570 | 2/20 | 0.54 |
| ▸ | CA2 | P00918 | 2/20 | 0.54 |
| ▸ | CA4 | P22748 | 2/20 | 0.54 |
| ▸ | CA14 | Q9ULX7 | 2/20 | 0.54 |
| ▸ | HMGB1 | P09429 | 1/20 | 0.54 |
| ▸ | CA6 | P23280 | 1/20 | 0.54 |
| ▸ | CA7 | P43166 | 1/20 | 0.54 |
| ▸ | NAPRT | Q6XQN6 | 1/20 | 0.54 |
| ▸ | MEN1 | O00255 | 5/20 | 0.52 |
| ▸ | KMT2A | Q03164 | 5/20 | 0.52 |
| ▸ | HSD17B10 | Q99714 | 7/20 | 0.47 |
| ▸ | MAPT | P10636 | 5/20 | 0.47 |
| ▸ | ALOX15 | P16050 | 4/20 | 0.47 |
| ▸ | POLB | P06746 | 2/20 | 0.47 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL30043535 | 0.97 | HPGD (0.56) | HPGDALDH1A1KDM4ESMN1; SMN2CA1 | |
| SCHEMBL61048 | 0.97 | HPGD (0.56) | HPGDALDH1A1KDM4ESMN1; SMN2CA1 | |
| SCHEMBL11209269 | 0.95 | HPGD (0.54) | HPGDALDH1A1KDM4ESMN1; SMN2CA1 | |
| SCHEMBL11206696 | 0.95 | HPGD (0.54) | HPGDALDH1A1KDM4ESMN1; SMN2CA1 | |
| SCHEMBL3626932 | 0.95 | HPGD (0.54) | HPGDALDH1A1KDM4ESMN1; SMN2CA1 | |
| SCHEMBL11210054 | 0.95 | HPGD (0.54) | HPGDALDH1A1KDM4ESMN1; SMN2CA1 | |
| SCHEMBL10726307 | 0.95 | HPGD (0.54) | HPGDALDH1A1KDM4ESMN1; SMN2CA1 | |
| SCHEMBL11208501 | 0.95 | HPGD (0.54) | HPGDALDH1A1KDM4ESMN1; SMN2CA1 | |
| SCHEMBL9335124 | 0.95 | HPGD (0.54) | HPGDALDH1A1KDM4ESMN1; SMN2CA1 | |
| SCHEMBL430368 | 0.95 | HPGD (0.54) | HPGDALDH1A1KDM4ESMN1; SMN2CA1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 7 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| JP-8119862-A | — | — | None | — | — | JP | disclosed |
| EP-3541368-B1 | IMAGEABLE PARTICLES, METHODS OF MAKING AND METHODS OF USE THEREOF | US HEALTH (US) | 2023-07-12 | — | — | EP | disclosed |
| US-11382990-B2 | Imageable polymers, methods of making and methods of use thereof | THE USA, AS REPRESENTED BY THE SECRETARY, DHHS (US) | 2022-07-12 | — | — | US | disclosed |
| US-20200197540-A1 | Imageable Polymers, Methods of Making and Methods of Use Thereof | THE UNITED STATES OF AMERICA, AS REPRESENTED BY THE SECRETARY, DEPARTMENT OF HEALTH AND HUMAN SERVICES | 2020-06-25 | — | — | US | disclosed |
| EP-3541368-A1 | IMAGEABLE PARTICLES, METHODS OF MAKING AND METHODS OF USE THEREOF | The United States of America, as represented by the Secretary, Department of Health and Human Services (US) | 2019-09-25 | — | — | EP | disclosed |
| WO-2018093566-A1 | IMAGEABLE PARTICLES, METHODS OF MAKING AND METHODS OF USE THEREOF | THE UNITED STATES OF AMERICA, AS REPRESENTED BY THE SECRETARY, DEPARTMENT OF HEALTH AND HUMAN SERVICES (US) | 2018-05-24 | — | — | WO | disclosed |
| JP-H08119862-A | BISMUTH COMPLEX AND ANTIBACTERIAL AGENT CONTAINING THE SAME | YASUSATO EIJI | 1996-05-14 | — | — | JP | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (2 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-11382990-B2 | Imageable polymers, methods of making and methods of use thereof | PUF60, PBRM1, PCBP1 | HPGD 1801/4885ALDH1A1 4268/4885KDM4E 1954/4885 |
| US-20200197540-A1 | Imageable Polymers, Methods of Making and Methods of Use Thereof | PUF60, PBRM1, PCBP1 | HPGD 1801/4885ALDH1A1 4268/4885KDM4E 1954/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.