Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | TSHR | P16473 | 5/20 | 0.54 |
| ▸ | ESR1 | P03372 | 4/20 | 0.54 |
| ▸ | MAPK1 | P28482 | 3/20 | 0.54 |
| ▸ | LMNA | P02545 | 1/20 | 0.54 |
| ▸ | CYP1A2 | P05177 | 1/20 | 0.54 |
| ▸ | CYP2D6 | P10635 | 1/20 | 0.54 |
| ▸ | CYP2C19 | P33261 | 1/20 | 0.54 |
| ▸ | NR1H2 | P55055 | 1/20 | 0.54 |
| ▸ | RNASEL | Q05823 | 1/20 | 0.54 |
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.54 |
| ▸ | CA12 | O43570 | 1/20 | 0.50 |
| ▸ | CA1 | P00915 | 1/20 | 0.50 |
| ▸ | CA2 | P00918 | 1/20 | 0.50 |
| ▸ | CA7 | P43166 | 1/20 | 0.50 |
| ▸ | CA9 | Q16790 | 1/20 | 0.50 |
| ▸ | CA14 | Q9ULX7 | 1/20 | 0.50 |
| ▸ | TDP1 | Q9NUW8 | 2/20 | 0.49 |
| ▸ | L3MBTL1 | Q9Y468 | 2/20 | 0.49 |
| ▸ | CYP3A4 | P08684 | 2/20 | 0.45 |
| ▸ | ALDH1A1 | P00352 | 2/20 | 0.45 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL9017666 | 0.87 | CA12 (0.68) | TSHRESR1NR1H2CA12CA1 | |
| SCHEMBL30456970 | 0.83 | CA12 (0.71) | TSHRESR1MAPK1LMNACYP1A2 | |
| SCHEMBL3063884 | 0.83 | CA12 (0.71) | TSHRESR1MAPK1LMNACYP1A2 | |
| SCHEMBL28363086 | 0.82 | TSHR (0.56) | TSHRESR1MAPK1LMNACYP3A4 | |
| SCHEMBL4397432 | 0.79 | CA12 (0.65) | TSHRESR1LMNACA12CA1 | |
| SCHEMBL4594973 | 0.79 | CA12 (0.69) | TSHRESR1MAPK1LMNACYP1A2 | |
| SCHEMBL17107306 | 0.78 | CA12 (0.67) | TSHRESR1MAPK1LMNACA12 | |
| SCHEMBL10581365 | 0.78 | CA12 (0.67) | TSHRESR1MAPK1LMNACA12 | |
| SCHEMBL495935 | 0.78 | CA12 (0.67) | TSHRESR1MAPK1LMNACA12 | |
| SCHEMBL31125332 | 0.78 | CA12 (0.67) | TSHRESR1MAPK1LMNACA12 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-5550205-A | MELT-POLYCONDENSING AROMATIC DIHYDROXY COMPOUNDS AND CARBONIC DIESTERS IN THE PRESENCE OF AN ALKALI METAL OR ALKALINE EARTH METAL CATALYST | GENERAL ELECTRIC COMPANY (US) | 1996-08-27 | — | — | US | disclosed |